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Hedgehog pathway inhibition in chondrosarcoma using the smoothened inhibitor IPI-926 directly inhibits sarcoma cell growth.
Mol Cancer Ther. 2014 May;13(5):1259-69. doi: 10.1158/1535-7163.MCT-13-0731. Epub 2014 Mar 14.
Mol Cancer Ther. 2014.
PMID: 24634412
Impact of the Smoothened inhibitor, IPI-926, on smoothened ciliary localization and Hedgehog pathway activity.
Peluso MO, Campbell VT, Harari JA, Tibbitts TT, Proctor JL, Whitebread N, Conley JM, White KF, Kutok JL, Read MA, McGovern K, Faia KL.
Peluso MO, et al. Among authors: campbell vt.
PLoS One. 2014 Mar 7;9(3):e90534. doi: 10.1371/journal.pone.0090534. eCollection 2014.
PLoS One. 2014.
PMID: 24608250
Free PMC article.
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Involvement and targeted intervention of dysregulated Hedgehog signaling in osteosarcoma.
Lo WW, Wunder JS, Dickson BC, Campbell V, McGovern K, Alman BA, Andrulis IL.
Lo WW, et al.
Cancer. 2014 Feb 15;120(4):537-47. doi: 10.1002/cncr.28439. Epub 2013 Oct 21.
Cancer. 2014.
PMID: 24151134
Free article.
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The pre-clinical absorption, distribution, metabolism and excretion properties of IPI-926, an orally bioavailable antagonist of the hedgehog signal transduction pathway.
Smith S, Hoyt J, Whitebread N, Manna J, Peluso M, Faia K, Campbell V, Tremblay M, Nair S, Grogan M, Castro A, Campbell M, Ferguson J, Arsenault B, Nevejans J, Carter B, Lee J, Dunbar J, McGovern K, Read M, Adams J, Constan A, Loewen G, Sydor J, Palombella V, Soglia J.
Smith S, et al.
Xenobiotica. 2013 Oct;43(10):875-85. doi: 10.3109/00498254.2013.780671. Epub 2013 Mar 25.
Xenobiotica. 2013.
PMID: 23527529
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Rethinking Inspiratory Pressure Augmentation in Spontaneous Breathing Trials.
Goligher EC, Detsky ME, Sklar MC, Campbell VT, Greco P, Amaral ACKB, Ferguson ND, Brochard LJ.
Goligher EC, et al. Among authors: campbell vt.
Chest. 2017 Jun;151(6):1399-1400. doi: 10.1016/j.chest.2017.02.033.
Chest. 2017.
PMID: 28599934
No abstract available.
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