Laties AM - Search Results

1

Rescue of compromised lysosomes enhances degradation of photoreceptor outer segments and reduces lipofuscin-like autofluorescence in retinal pigmented epithelial cells.

Guha S, Liu J, Baltazar G, Laties AM, Mitchell CH. Guha S, et al. Among authors: laties am. Adv Exp Med Biol. 2014;801:105-11. doi: 10.1007/978-1-4614-3209-8_14. Adv Exp Med Biol. 2014. PMID: 24664687 Free PMC article. Review.

2

Restoration of lysosomal pH in RPE cells from cultured human and ABCA4(-/-) mice: pharmacologic approaches and functional recovery.

Liu J, Lu W, Reigada D, Nguyen J, Laties AM, Mitchell CH. Liu J, et al. Among authors: laties am. Invest Ophthalmol Vis Sci. 2008 Feb;49(2):772-80. doi: 10.1167/iovs.07-0675. Invest Ophthalmol Vis Sci. 2008. PMID: 18235027 Free PMC article.

3

Cystic fibrosis transmembrane conductance regulator contributes to reacidification of alkalinized lysosomes in RPE cells.

Liu J, Lu W, Guha S, Baltazar GC, Coffey EE, Laties AM, Rubenstein RC, Reenstra WW, Mitchell CH. Liu J, et al. Among authors: laties am. Am J Physiol Cell Physiol. 2012 Jul 15;303(2):C160-9. doi: 10.1152/ajpcell.00278.2011. Epub 2012 May 9. Am J Physiol Cell Physiol. 2012. PMID: 22572847 Free PMC article.

4

Stimulation of the D5 dopamine receptor acidifies the lysosomal pH of retinal pigmented epithelial cells and decreases accumulation of autofluorescent photoreceptor debris.

Guha S, Baltazar GC, Tu LA, Liu J, Lim JC, Lu W, Argall A, Boesze-Battaglia K, Laties AM, Mitchell CH. Guha S, et al. Among authors: laties am. J Neurochem. 2012 Aug;122(4):823-33. doi: 10.1111/j.1471-4159.2012.07804.x. Epub 2012 Jun 27. J Neurochem. 2012. PMID: 22639870 Free PMC article.

5

Acidic nanoparticles are trafficked to lysosomes and restore an acidic lysosomal pH and degradative function to compromised ARPE-19 cells.

Baltazar GC, Guha S, Lu W, Lim J, Boesze-Battaglia K, Laties AM, Tyagi P, Kompella UB, Mitchell CH. Baltazar GC, et al. Among authors: laties am. PLoS One. 2012;7(12):e49635. doi: 10.1371/journal.pone.0049635. Epub 2012 Dec 18. PLoS One. 2012. PMID: 23272048 Free PMC article.

6

Lysosomal alkalinization, lipid oxidation, and reduced phagosome clearance triggered by activation of the P2X7 receptor.

Guha S, Baltazar GC, Coffey EE, Tu LA, Lim JC, Beckel JM, Patel S, Eysteinsson T, Lu W, O'Brien-Jenkins A, Laties AM, Mitchell CH. Guha S, et al. Among authors: laties am. FASEB J. 2013 Nov;27(11):4500-9. doi: 10.1096/fj.13-236166. Epub 2013 Aug 20. FASEB J. 2013. PMID: 23964074 Free PMC article.

7

Approaches for detecting lysosomal alkalinization and impaired degradation in fresh and cultured RPE cells: evidence for a role in retinal degenerations.

Guha S, Coffey EE, Lu W, Lim JC, Beckel JM, Laties AM, Boesze-Battaglia K, Mitchell CH. Guha S, et al. Among authors: laties am. Exp Eye Res. 2014 Sep;126:68-76. doi: 10.1016/j.exer.2014.05.013. Exp Eye Res. 2014. PMID: 25152362 Free PMC article. Review.

8

Lysosomal alkalization and dysfunction in human fibroblasts with the Alzheimer's disease-linked presenilin 1 A246E mutation can be reversed with cAMP.

Coffey EE, Beckel JM, Laties AM, Mitchell CH. Coffey EE, et al. Among authors: laties am. Neuroscience. 2014 Mar 28;263:111-24. doi: 10.1016/j.neuroscience.2014.01.001. Epub 2014 Jan 10. Neuroscience. 2014. PMID: 24418614 Free PMC article.

9

Degradation of extracellular ATP by the retinal pigment epithelium.

Reigada D, Lu W, Zhang X, Friedman C, Pendrak K, McGlinn A, Stone RA, Laties AM, Mitchell CH. Reigada D, et al. Among authors: laties am. Am J Physiol Cell Physiol. 2005 Sep;289(3):C617-24. doi: 10.1152/ajpcell.00542.2004. Epub 2005 Apr 27. Am J Physiol Cell Physiol. 2005. PMID: 15857904 Free article.

10

The A3 adenosine receptor attenuates the calcium rise triggered by NMDA receptors in retinal ganglion cells.

Zhang M, Hu H, Zhang X, Lu W, Lim J, Eysteinsson T, Jacobson KA, Laties AM, Mitchell CH. Zhang M, et al. Among authors: laties am. Neurochem Int. 2010 Jan;56(1):35-41. doi: 10.1016/j.neuint.2009.08.011. Epub 2009 Aug 31. Neurochem Int. 2010. PMID: 19723551 Free PMC article.

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