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Glucose-based spiro-isoxazolines: a new family of potent glycogen phosphorylase inhibitors.
Benltifa M, Hayes JM, Vidal S, Gueyrard D, Goekjian PG, Praly JP, Kizilis G, Tiraidis C, Alexacou KM, Chrysina ED, Zographos SE, Leonidas DD, Archontis G, Oikonomakos NG. Benltifa M, et al. Among authors: praly jp. Bioorg Med Chem. 2009 Oct 15;17(20):7368-80. doi: 10.1016/j.bmc.2009.08.060. Epub 2009 Sep 2. Bioorg Med Chem. 2009. PMID: 19781947
Glucose-derived spiro-isoxazolines are anti-hyperglycemic agents against type 2 diabetes through glycogen phosphorylase inhibition.
Goyard D, Kónya B, Chajistamatiou AS, Chrysina ED, Leroy J, Balzarin S, Tournier M, Tousch D, Petit P, Duret C, Maurel P, Somsák L, Docsa T, Gergely P, Praly JP, Azay-Milhau J, Vidal S. Goyard D, et al. Among authors: praly jp. Eur J Med Chem. 2016 Jan 27;108:444-454. doi: 10.1016/j.ejmech.2015.12.004. Epub 2015 Dec 10. Eur J Med Chem. 2016. PMID: 26708111
47 results