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Lysine glutarylation is a protein posttranslational modification regulated by SIRT5.
Tan M, Peng C, Anderson KA, Chhoy P, Xie Z, Dai L, Park J, Chen Y, Huang H, Zhang Y, Ro J, Wagner GR, Green MF, Madsen AS, Schmiesing J, Peterson BS, Xu G, Ilkayeva OR, Muehlbauer MJ, Braulke T, Mühlhausen C, Backos DS, Olsen CA, McGuire PJ, Pletcher SD, Lombard DB, Hirschey MD, Zhao Y. Tan M, et al. Among authors: wagner gr. Cell Metab. 2014 Apr 1;19(4):605-17. doi: 10.1016/j.cmet.2014.03.014. Cell Metab. 2014. PMID: 24703693 Free PMC article.
A Prob(e)able Route to Lysine Acylation.
Wagner GR, Hirschey MD. Wagner GR, et al. Cell Chem Biol. 2017 Feb 16;24(2):126-128. doi: 10.1016/j.chembiol.2017.01.011. Cell Chem Biol. 2017. PMID: 28212757 Free PMC article.
SIRT4 Is a Lysine Deacylase that Controls Leucine Metabolism and Insulin Secretion.
Anderson KA, Huynh FK, Fisher-Wellman K, Stuart JD, Peterson BS, Douros JD, Wagner GR, Thompson JW, Madsen AS, Green MF, Sivley RM, Ilkayeva OR, Stevens RD, Backos DS, Capra JA, Olsen CA, Campbell JE, Muoio DM, Grimsrud PA, Hirschey MD. Anderson KA, et al. Among authors: wagner gr. Cell Metab. 2017 Apr 4;25(4):838-855.e15. doi: 10.1016/j.cmet.2017.03.003. Cell Metab. 2017. PMID: 28380376 Free PMC article.
Statin therapy inhibits fatty acid synthase via dynamic protein modifications.
Trub AG, Wagner GR, Anderson KA, Crown SB, Zhang GF, Thompson JW, Ilkayeva OR, Stevens RD, Grimsrud PA, Kulkarni RA, Backos DS, Meier JL, Hirschey MD. Trub AG, et al. Among authors: wagner gr. Nat Commun. 2022 May 10;13(1):2542. doi: 10.1038/s41467-022-30060-w. Nat Commun. 2022. PMID: 35538051 Free PMC article.
SnapShot: Mammalian Sirtuins.
Anderson KA, Green MF, Huynh FK, Wagner GR, Hirschey MD. Anderson KA, et al. Among authors: wagner gr. Cell. 2014 Nov 6;159(4):956-956.e1. doi: 10.1016/j.cell.2014.10.045. Cell. 2014. PMID: 25417168 Free PMC article.
Respiratory Phenomics across Multiple Models of Protein Hyperacylation in Cardiac Mitochondria Reveals a Marginal Impact on Bioenergetics.
Fisher-Wellman KH, Draper JA, Davidson MT, Williams AS, Narowski TM, Slentz DH, Ilkayeva OR, Stevens RD, Wagner GR, Najjar R, Hirschey MD, Thompson JW, Olson DP, Kelly DP, Koves TR, Grimsrud PA, Muoio DM. Fisher-Wellman KH, et al. Among authors: wagner gr. Cell Rep. 2019 Feb 5;26(6):1557-1572.e8. doi: 10.1016/j.celrep.2019.01.057. Cell Rep. 2019. PMID: 30726738 Free PMC article.
127 results