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Probing SH2-domains using Inhibitor Affinity Purification (IAP).
Höfener M, Heinzlmeir S, Kuster B, Sewald N. Höfener M, et al. Among authors: heinzlmeir s. Proteome Sci. 2014 Jul 16;12:41. doi: 10.1186/1477-5956-12-41. eCollection 2014. Proteome Sci. 2014. PMID: 25067910 Free PMC article.
Optimized chemical proteomics assay for kinase inhibitor profiling.
Médard G, Pachl F, Ruprecht B, Klaeger S, Heinzlmeir S, Helm D, Qiao H, Ku X, Wilhelm M, Kuehne T, Wu Z, Dittmann A, Hopf C, Kramer K, Kuster B. Médard G, et al. Among authors: heinzlmeir s. J Proteome Res. 2015 Mar 6;14(3):1574-86. doi: 10.1021/pr5012608. Epub 2015 Feb 20. J Proteome Res. 2015. PMID: 25660469
Evaluation of Kinase Activity Profiling Using Chemical Proteomics.
Ruprecht B, Zecha J, Heinzlmeir S, Médard G, Lemeer S, Kuster B. Ruprecht B, et al. Among authors: heinzlmeir s. ACS Chem Biol. 2015 Dec 18;10(12):2743-52. doi: 10.1021/acschembio.5b00616. Epub 2015 Oct 5. ACS Chem Biol. 2015. PMID: 26378887
Chemical Proteomics Reveals Ferrochelatase as a Common Off-target of Kinase Inhibitors.
Klaeger S, Gohlke B, Perrin J, Gupta V, Heinzlmeir S, Helm D, Qiao H, Bergamini G, Handa H, Savitski MM, Bantscheff M, Médard G, Preissner R, Kuster B. Klaeger S, et al. Among authors: heinzlmeir s. ACS Chem Biol. 2016 May 20;11(5):1245-54. doi: 10.1021/acschembio.5b01063. Epub 2016 Feb 25. ACS Chem Biol. 2016. PMID: 26863403
Chemoproteomics-Aided Medicinal Chemistry for the Discovery of EPHA2 Inhibitors.
Heinzlmeir S, Lohse J, Treiber T, Kudlinzki D, Linhard V, Gande SL, Sreeramulu S, Saxena K, Liu X, Wilhelm M, Schwalbe H, Kuster B, Médard G. Heinzlmeir S, et al. ChemMedChem. 2017 Jun 21;12(12):999-1011. doi: 10.1002/cmdc.201700217. Epub 2017 Jun 12. ChemMedChem. 2017. PMID: 28544567
The target landscape of clinical kinase drugs.
Klaeger S, Heinzlmeir S, Wilhelm M, Polzer H, Vick B, Koenig PA, Reinecke M, Ruprecht B, Petzoldt S, Meng C, Zecha J, Reiter K, Qiao H, Helm D, Koch H, Schoof M, Canevari G, Casale E, Depaolini SR, Feuchtinger A, Wu Z, Schmidt T, Rueckert L, Becker W, Huenges J, Garz AK, Gohlke BO, Zolg DP, Kayser G, Vooder T, Preissner R, Hahne H, Tõnisson N, Kramer K, Götze K, Bassermann F, Schlegl J, Ehrlich HC, Aiche S, Walch A, Greif PA, Schneider S, Felder ER, Ruland J, Médard G, Jeremias I, Spiekermann K, Kuster B. Klaeger S, et al. Among authors: heinzlmeir s. Science. 2017 Dec 1;358(6367):eaan4368. doi: 10.1126/science.aan4368. Science. 2017. PMID: 29191878 Free PMC article.
35 results