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Page 1
Design of novel multiple-acting ligands towards SERT and 5-HT2C receptors.
Eliás O, Agai-Csongor E, Domány G, Keserű GM, Gere A, Kiss B, Hellinger E, Vastag M, Gyertyán I. Eliás O, et al. Among authors: kiss b. Bioorg Med Chem Lett. 2014 May 1;24(9):2118-22. doi: 10.1016/j.bmcl.2014.03.043. Epub 2014 Mar 24. Bioorg Med Chem Lett. 2014. PMID: 24717153
Novel sulfonamides having dual dopamine D2 and D3 receptor affinity show in vivo antipsychotic efficacy with beneficial cognitive and EPS profile.
Agai-Csongor E, Nógrádi K, Galambos J, Vágó I, Bielik A, Magdó I, Ignácz-Szendrei G, Keseru GM, Greiner I, Laszlovszky I, Schmidt E, Kiss B, Sághy K, Laszy J, Gyertyán I, Zájer-Balázs M, Gémesi L, Domány G. Agai-Csongor E, et al. Among authors: kiss b. Bioorg Med Chem Lett. 2007 Oct 1;17(19):5340-4. doi: 10.1016/j.bmcl.2007.08.015. Epub 2007 Aug 15. Bioorg Med Chem Lett. 2007. PMID: 17720494
Hit-to-lead optimization of disubstituted oxadiazoles and tetrazoles as mGluR5 NAMs.
Wágner G, Wéber C, Nyéki O, Nógrádi K, Bielik A, Molnár L, Bobok A, Horváth A, Kiss B, Kolok S, Nagy J, Kurkó D, Gál K, Greiner I, Szombathelyi Z, Keseru GM, Domány G. Wágner G, et al. Among authors: kiss b. Bioorg Med Chem Lett. 2010 Jun 15;20(12):3737-41. doi: 10.1016/j.bmcl.2010.04.075. Epub 2010 Apr 22. Bioorg Med Chem Lett. 2010. PMID: 20483612
Carbamoyloximes as novel non-competitive mGlu5 receptor antagonists.
Galambos J, Wágner G, Nógrádi K, Bielik A, Molnár L, Bobok A, Horváth A, Kiss B, Kolok S, Nagy J, Kurkó D, Bakk ML, Vastag M, Sághy K, Gyertyán I, Gál K, Greiner I, Szombathelyi Z, Keseru GM, Domány G. Galambos J, et al. Among authors: kiss b. Bioorg Med Chem Lett. 2010 Aug 1;20(15):4371-5. doi: 10.1016/j.bmcl.2010.06.075. Epub 2010 Jun 17. Bioorg Med Chem Lett. 2010. PMID: 20615697
Discovery of cariprazine (RGH-188): a novel antipsychotic acting on dopamine D3/D2 receptors.
Agai-Csongor E, Domány G, Nógrádi K, Galambos J, Vágó I, Keserű GM, Greiner I, Laszlovszky I, Gere A, Schmidt E, Kiss B, Vastag M, Tihanyi K, Sághy K, Laszy J, Gyertyán I, Zájer-Balázs M, Gémesi L, Kapás M, Szombathelyi Z. Agai-Csongor E, et al. Among authors: kiss b. Bioorg Med Chem Lett. 2012 May 15;22(10):3437-40. doi: 10.1016/j.bmcl.2012.03.104. Epub 2012 Apr 4. Bioorg Med Chem Lett. 2012. PMID: 22537450
The influence of 5-HT(2A) activity on a 5-HT(2C) specific in vivo assay used for early identification of multiple acting SERT and 5-HT(2C) receptor ligands.
Éliás O, Nógrádi K, Domány G, Szakács Z, Kóti J, Szántay C Jr, Tarcsay Á, Keserű GM, Gere A, Kiss B, Kurkó D, Kolok S, Némethy Z, Kapui Z, Hellinger É, Vastag M, Sághy K, Kedves R, Gyertyán I. Éliás O, et al. Among authors: kiss b. Bioorg Med Chem Lett. 2016 Feb 1;26(3):914-920. doi: 10.1016/j.bmcl.2015.12.071. Epub 2015 Dec 21. Bioorg Med Chem Lett. 2016. PMID: 26748694
472 results