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Low and moderate doses of ionizing radiation up to 2 Gy modulate transmigration and chemotaxis of activated macrophages, provoke an anti-inflammatory cytokine milieu, but do not impact upon viability and phagocytic function.
Wunderlich R, Ernst A, Rödel F, Fietkau R, Ott O, Lauber K, Frey B, Gaipl US. Wunderlich R, et al. Among authors: ott o. Clin Exp Immunol. 2015 Jan;179(1):50-61. doi: 10.1111/cei.12344. Clin Exp Immunol. 2015. PMID: 24730395 Free PMC article.
Low-Dose Radiotherapy Leads to a Systemic Anti-Inflammatory Shift in the Pre-Clinical K/BxN Serum Transfer Model and Reduces Osteoarthritic Pain in Patients.
Weissmann T, Rückert M, Zhou JG, Seeling M, Lettmaier S, Donaubauer AJ, Nimmerjahn F, Ott OJ, Hecht M, Putz F, Fietkau R, Frey B, Gaipl US, Deloch L. Weissmann T, et al. Front Immunol. 2022 Jan 3;12:777792. doi: 10.3389/fimmu.2021.777792. eCollection 2021. Front Immunol. 2022. PMID: 35046940 Free PMC article. Clinical Trial.
155 results