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Bioactivation of the human carcinogen aristolochic acid.
Sidorenko VS, Attaluri S, Zaitseva I, Iden CR, Dickman KG, Johnson F, Grollman AP. Sidorenko VS, et al. Among authors: grollman ap. Carcinogenesis. 2014 Aug;35(8):1814-22. doi: 10.1093/carcin/bgu095. Epub 2014 Apr 17. Carcinogenesis. 2014. PMID: 24743514 Free PMC article.
Cytochrome P450 1A2 detoxicates aristolochic acid in the mouse.
Rosenquist TA, Einolf HJ, Dickman KG, Wang L, Smith A, Grollman AP. Rosenquist TA, et al. Among authors: grollman ap. Drug Metab Dispos. 2010 May;38(5):761-8. doi: 10.1124/dmd.110.032201. Epub 2010 Feb 17. Drug Metab Dispos. 2010. PMID: 20164109 Free PMC article.
Human liver-kidney model elucidates the mechanisms of aristolochic acid nephrotoxicity.
Chang SY, Weber EJ, Sidorenko VS, Chapron A, Yeung CK, Gao C, Mao Q, Shen D, Wang J, Rosenquist TA, Dickman KG, Neumann T, Grollman AP, Kelly EJ, Himmelfarb J, Eaton DL. Chang SY, et al. Among authors: grollman ap. JCI Insight. 2017 Nov 16;2(22):e95978. doi: 10.1172/jci.insight.95978. eCollection 2017 Nov 16. JCI Insight. 2017. PMID: 29202460 Free PMC article.
237 results