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Identification of novel nuclear targets of human thioredoxin 1.
Wu C, Jain MR, Li Q, Oka S, Li W, Kong AN, Nagarajan N, Sadoshima J, Simmons WJ, Li H. Wu C, et al. Among authors: nagarajan n. Mol Cell Proteomics. 2014 Dec;13(12):3507-18. doi: 10.1074/mcp.M114.040931. Epub 2014 Sep 17. Mol Cell Proteomics. 2014. PMID: 25231459 Free PMC article.
Master redox regulator Trx1 upregulates SMYD1 & modulates lysine methylation.
Liu T, Wu C, Jain MR, Nagarajan N, Yan L, Dai H, Cui C, Baykal A, Pan S, Ago T, Sadoshima J, Li H. Liu T, et al. Among authors: nagarajan n. Biochim Biophys Acta. 2015 Dec;1854(12):1816-1822. doi: 10.1016/j.bbapap.2015.09.006. Epub 2015 Sep 26. Biochim Biophys Acta. 2015. PMID: 26410624 Free PMC article.
Thioredoxin-1 maintains mechanistic target of rapamycin (mTOR) function during oxidative stress in cardiomyocytes.
Oka SI, Hirata T, Suzuki W, Naito D, Chen Y, Chin A, Yaginuma H, Saito T, Nagarajan N, Zhai P, Bhat S, Schesing K, Shao D, Hirabayashi Y, Yodoi J, Sciarretta S, Sadoshima J. Oka SI, et al. Among authors: nagarajan n. J Biol Chem. 2017 Nov 17;292(46):18988-19000. doi: 10.1074/jbc.M117.807735. Epub 2017 Sep 22. J Biol Chem. 2017. PMID: 28939765 Free PMC article.
HAX-1 regulates SERCA2a oxidation and degradation.
Bidwell PA, Liu GS, Nagarajan N, Lam CK, Haghighi K, Gardner G, Cai WF, Zhao W, Mugge L, Vafiadaki E, Sanoudou D, Rubinstein J, Lebeche D, Hajjar R, Sadoshima J, Kranias EG. Bidwell PA, et al. Among authors: nagarajan n. J Mol Cell Cardiol. 2018 Jan;114:220-233. doi: 10.1016/j.yjmcc.2017.11.014. Epub 2017 Nov 21. J Mol Cell Cardiol. 2018. PMID: 29169992 Free PMC article.
The importance of autophagy in cardioprotection.
Sciarretta S, Yee D, Shenoy V, Nagarajan N, Sadoshima J. Sciarretta S, et al. Among authors: nagarajan n. High Blood Press Cardiovasc Prev. 2014 Mar;21(1):21-8. doi: 10.1007/s40292-013-0029-9. Epub 2013 Nov 14. High Blood Press Cardiovasc Prev. 2014. PMID: 24235024 Review.
mTORC2 regulates cardiac response to stress by inhibiting MST1.
Sciarretta S, Zhai P, Maejima Y, Del Re DP, Nagarajan N, Yee D, Liu T, Magnuson MA, Volpe M, Frati G, Li H, Sadoshima J. Sciarretta S, et al. Among authors: nagarajan n. Cell Rep. 2015 Apr 7;11(1):125-36. doi: 10.1016/j.celrep.2015.03.010. Epub 2015 Apr 2. Cell Rep. 2015. PMID: 25843706 Free PMC article.
261 results