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CCR5/CD4/CXCR4 oligomerization prevents HIV-1 gp120IIIB binding to the cell surface.
Martínez-Muñoz L, Barroso R, Dyrhaug SY, Navarro G, Lucas P, Soriano SF, Vega B, Costas C, Muñoz-Fernández MÁ, Santiago C, Rodríguez Frade JM, Franco R, Mellado M. Martínez-Muñoz L, et al. Among authors: lucas p. Proc Natl Acad Sci U S A. 2014 May 13;111(19):E1960-9. doi: 10.1073/pnas.1322887111. Epub 2014 Apr 28. Proc Natl Acad Sci U S A. 2014. PMID: 24778234 Free PMC article.
HIV-1 infection through the CCR5 receptor is blocked by receptor dimerization.
Vila-Coro AJ, Mellado M, Martín de Ana A, Lucas P, del Real G, Martínez-A C, Rodríguez-Frade JM. Vila-Coro AJ, et al. Among authors: lucas p. Proc Natl Acad Sci U S A. 2000 Mar 28;97(7):3388-93. doi: 10.1073/pnas.97.7.3388. Proc Natl Acad Sci U S A. 2000. PMID: 10725362 Free PMC article.
Blocking of HIV-1 infection by targeting CD4 to nonraft membrane domains.
Del Real G, Jiménez-Baranda S, Lacalle RA, Mira E, Lucas P, Gómez-Moutón C, Carrera AC, Martínez-A C, Mañes S. Del Real G, et al. Among authors: lucas p. J Exp Med. 2002 Aug 5;196(3):293-301. doi: 10.1084/jem.20020308. J Exp Med. 2002. PMID: 12163558 Free PMC article.
SOCS up-regulation mobilizes autologous stem cells through CXCR4 blockade.
Pello OM, Moreno-Ortiz Mdel C, Rodríguez-Frade JM, Martínez-Muñoz L, Lucas D, Gómez L, Lucas P, Samper E, Aracil M, Martínez C, Bernad A, Mellado M. Pello OM, et al. Among authors: lucas p, lucas d. Blood. 2006 Dec 1;108(12):3928-37. doi: 10.1182/blood-2006-02-006353. Epub 2006 Aug 15. Blood. 2006. PMID: 16912231 Free article.
Dynamic regulation of CXCR1 and CXCR2 homo- and heterodimers.
Martínez Muñoz L, Lucas P, Navarro G, Checa AI, Franco R, Martínez-A C, Rodríguez-Frade JM, Mellado M. Martínez Muñoz L, et al. Among authors: lucas p. J Immunol. 2009 Dec 1;183(11):7337-46. doi: 10.4049/jimmunol.0901802. Epub 2009 Nov 4. J Immunol. 2009. PMID: 19890050
1,124 results