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Modeling human gastrointestinal inflammatory diseases using microphysiological culture systems.
Exp Biol Med (Maywood). 2014 Sep;239(9):1108-23. doi: 10.1177/1535370214529388. Epub 2014 Apr 29.
Exp Biol Med (Maywood). 2014.
PMID: 24781339
Free PMC article.
Review.
Modeling inflammation and oxidative stress in gastrointestinal disease development using novel organotypic culture systems.
Hartman KG, Bortner JD, Falk GW, Yu J, Martín MG, Rustgi AK, Lynch JP.
Hartman KG, et al.
Stem Cell Res Ther. 2013;4 Suppl 1(Suppl 1):S5. doi: 10.1186/scrt366. Epub 2013 Dec 20.
Stem Cell Res Ther. 2013.
PMID: 24564965
Free PMC article.
Review.
Item in Clipboard
Covalent small molecule inhibitors of Ca(2+)-bound S100B.
Cavalier MC, Pierce AD, Wilder PT, Alasady MJ, Hartman KG, Neau DB, Foley TL, Jadhav A, Maloney DJ, Simeonov A, Toth EA, Weber DJ.
Cavalier MC, et al. Among authors: hartman kg.
Biochemistry. 2014 Oct 28;53(42):6628-40. doi: 10.1021/bi5005552. Epub 2014 Oct 14.
Biochemistry. 2014.
PMID: 25268459
Free PMC article.
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Complex formation between S100B protein and the p90 ribosomal S6 kinase (RSK) in malignant melanoma is calcium-dependent and inhibits extracellular signal-regulated kinase (ERK)-mediated phosphorylation of RSK.
Hartman KG, Vitolo MI, Pierce AD, Fox JM, Shapiro P, Martin SS, Wilder PT, Weber DJ.
Hartman KG, et al.
J Biol Chem. 2014 May 2;289(18):12886-95. doi: 10.1074/jbc.M114.561613. Epub 2014 Mar 13.
J Biol Chem. 2014.
PMID: 24627490
Free PMC article.
Item in Clipboard
Structure-Based Discovery of a Novel Pentamidine-Related Inhibitor of the Calcium-Binding Protein S100B.
McKnight LE, Raman EP, Bezawada P, Kudrimoti S, Wilder PT, Hartman KG, Godoy-Ruiz R, Toth EA, Coop A, Mackerell AD Jr, Weber DJ.
McKnight LE, et al. Among authors: hartman kg.
ACS Med Chem Lett. 2012 Dec 13;3(12):975-979. doi: 10.1021/ml300166s. Epub 2012 Sep 25.
ACS Med Chem Lett. 2012.
PMID: 23264854
Free PMC article.
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The evolution of S100B inhibitors for the treatment of malignant melanoma.
Hartman KG, McKnight LE, Liriano MA, Weber DJ.
Hartman KG, et al.
Future Med Chem. 2013 Jan;5(1):97-109. doi: 10.4155/fmc.12.191.
Future Med Chem. 2013.
PMID: 23256816
Free PMC article.
Review.
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