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Development of a novel, CNS-penetrant, metabotropic glutamate receptor 3 (mGlu3) NAM probe (ML289) derived from a closely related mGlu5 PAM.
Sheffler DJ, Wenthur CJ, Bruner JA, Carrington SJ, Vinson PN, Gogi KK, Blobaum AL, Morrison RD, Vamos M, Cosford ND, Stauffer SR, Daniels JS, Niswender CM, Conn PJ, Lindsley CW. Sheffler DJ, et al. Among authors: wenthur cj. Bioorg Med Chem Lett. 2012 Jun 15;22(12):3921-5. doi: 10.1016/j.bmcl.2012.04.112. Epub 2012 Apr 30. Bioorg Med Chem Lett. 2012. PMID: 22607673 Free PMC article.
Classics in chemical neuroscience: clozapine.
Wenthur CJ, Lindsley CW. Wenthur CJ, et al. ACS Chem Neurosci. 2013 Jul 17;4(7):1018-25. doi: 10.1021/cn400121z. ACS Chem Neurosci. 2013. PMID: 24047509 Free PMC article. Review.
Drugs for allosteric sites on receptors.
Wenthur CJ, Gentry PR, Mathews TP, Lindsley CW. Wenthur CJ, et al. Annu Rev Pharmacol Toxicol. 2014;54:165-84. doi: 10.1146/annurev-pharmtox-010611-134525. Epub 2013 Oct 2. Annu Rev Pharmacol Toxicol. 2014. PMID: 24111540 Free PMC article. Review.
Classics in Chemical Neuroscience: Methylphenidate.
Wenthur CJ. Wenthur CJ. ACS Chem Neurosci. 2016 Aug 17;7(8):1030-40. doi: 10.1021/acschemneuro.6b00199. Epub 2016 Jul 25. ACS Chem Neurosci. 2016. PMID: 27409720 Review.
Classics in Chemical Neuroscience: Buprenorphine.
Kyzer JL, Wenthur CJ. Kyzer JL, et al. Among authors: wenthur cj. ACS Chem Neurosci. 2020 May 20;11(10):1385-1399. doi: 10.1021/acschemneuro.0c00100. Epub 2020 Apr 29. ACS Chem Neurosci. 2020. PMID: 32302475
33 results