Franks LN - Search Results

1

Characterization of the intrinsic activity for a novel class of cannabinoid receptor ligands: Indole quinuclidine analogs.

Franks LN, Ford BM, Madadi NR, Penthala NR, Crooks PA, Prather PL. Franks LN, et al. Eur J Pharmacol. 2014 Aug 15;737:140-8. doi: 10.1016/j.ejphar.2014.05.007. Epub 2014 May 20. Eur J Pharmacol. 2014. PMID: 24858620 Free PMC article.

2

Human metabolites of synthetic cannabinoids JWH-018 and JWH-073 bind with high affinity and act as potent agonists at cannabinoid type-2 receptors.

Rajasekaran M, Brents LK, Franks LN, Moran JH, Prather PL. Rajasekaran M, et al. Among authors: franks ln. Toxicol Appl Pharmacol. 2013 Jun 1;269(2):100-8. doi: 10.1016/j.taap.2013.03.012. Epub 2013 Mar 26. Toxicol Appl Pharmacol. 2013. PMID: 23537664 Free PMC article.

3

Design, synthesis, and biological evaluation of aminoalkylindole derivatives as cannabinoid receptor ligands with potential for treatment of alcohol abuse.

Vasiljevik T, Franks LN, Ford BM, Douglas JT, Prather PL, Fantegrossi WE, Prisinzano TE. Vasiljevik T, et al. Among authors: franks ln. J Med Chem. 2013 Jun 13;56(11):4537-50. doi: 10.1021/jm400268b. Epub 2013 May 22. J Med Chem. 2013. PMID: 23631463 Free PMC article.

4

CB1 and CB2 receptors are novel molecular targets for Tamoxifen and 4OH-Tamoxifen.

Prather PL, FrancisDevaraj F, Dates CR, Greer AK, Bratton SM, Ford BM, Franks LN, Radominska-Pandya A. Prather PL, et al. Among authors: franks ln. Biochem Biophys Res Commun. 2013 Nov 15;441(2):339-43. doi: 10.1016/j.bbrc.2013.10.057. Epub 2013 Oct 19. Biochem Biophys Res Commun. 2013. PMID: 24148245 Free PMC article.

5

Tamoxifen Isomers and Metabolites Exhibit Distinct Affinity and Activity at Cannabinoid Receptors: Potential Scaffold for Drug Development.

Ford BM, Franks LN, Radominska-Pandya A, Prather PL. Ford BM, et al. Among authors: franks ln. PLoS One. 2016 Dec 9;11(12):e0167240. doi: 10.1371/journal.pone.0167240. eCollection 2016. PLoS One. 2016. PMID: 27936172 Free PMC article.

6

Selective Estrogen Receptor Modulators: Cannabinoid Receptor Inverse Agonists with Differential CB1 and CB2 Selectivity.

Franks LN, Ford BM, Prather PL. Franks LN, et al. Front Pharmacol. 2016 Dec 22;7:503. doi: 10.3389/fphar.2016.00503. eCollection 2016. Front Pharmacol. 2016. PMID: 28066250 Free PMC article.

7

Characterization of structurally novel G protein biased CB₁ agonists: Implications for drug development.

Ford BM, Franks LN, Tai S, Fantegrossi WE, Stahl EL, Berquist MD, Cabanlong CV, Wilson CD, Penthala NR, Crooks PA, Prather PL. Ford BM, et al. Among authors: franks ln. Pharmacol Res. 2017 Nov;125(Pt B):161-177. doi: 10.1016/j.phrs.2017.08.008. Epub 2017 Aug 23. Pharmacol Res. 2017. PMID: 28838808 Free PMC article.

8

The tamoxifen derivative ridaifen-B is a high affinity selective CB₂ receptor inverse agonist exhibiting anti-inflammatory and anti-osteoclastogenic effects.

Franks LN, Ford BM, Fujiwara T, Zhao H, Prather PL. Franks LN, et al. Toxicol Appl Pharmacol. 2018 Aug 15;353:31-42. doi: 10.1016/j.taap.2018.06.009. Epub 2018 Jun 12. Toxicol Appl Pharmacol. 2018. PMID: 29906493 Free PMC article.

9

Reduced Tolerance and Asymmetrical Crosstolerance to Effects of the Indole Quinuclidinone Analog PNR-4-20, a G Protein-Biased Cannabinoid 1 Receptor Agonist in Mice: Comparisons with Δ⁹-Tetrahydrocannabinol and JWH-018.

Ford BM, Cabanlong CV, Tai S, Franks LN, Penthala NR, Crooks PA, Prather PL, Fantegrossi WE. Ford BM, et al. Among authors: franks ln. J Pharmacol Exp Ther. 2019 May;369(2):259-269. doi: 10.1124/jpet.118.252965. Epub 2019 Mar 4. J Pharmacol Exp Ther. 2019. PMID: 30833484 Free PMC article.

10

Characterization of cannabinoid receptors expressed in Ewing sarcoma TC-71 and A-673 cells as potential targets for anti-cancer drug development.

Shoeib AM, Yarbrough AL, Ford BM, Franks LN, Urbaniak A, Hensley LL, Benson LN, Mu S, Radominska-Pandya A, Prather PL. Shoeib AM, et al. Among authors: franks ln. Life Sci. 2021 Nov 15;285:119993. doi: 10.1016/j.lfs.2021.119993. Epub 2021 Sep 28. Life Sci. 2021. PMID: 34592231 Free PMC article.

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