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Human memory T cells from the bone marrow are resting and maintain long-lasting systemic memory.
Okhrimenko A, Grün JR, Westendorf K, Fang Z, Reinke S, von Roth P, Wassilew G, Kühl AA, Kudernatsch R, Demski S, Scheibenbogen C, Tokoyoda K, McGrath MA, Raftery MJ, Schönrich G, Serra A, Chang HD, Radbruch A, Dong J. Okhrimenko A, et al. Among authors: westendorf k. Proc Natl Acad Sci U S A. 2014 Jun 24;111(25):9229-34. doi: 10.1073/pnas.1318731111. Epub 2014 Jun 10. Proc Natl Acad Sci U S A. 2014. PMID: 24927527 Free PMC article. Clinical Trial.
Persistence of effector memory Th1 cells is regulated by Hopx.
Albrecht I, Niesner U, Janke M, Menning A, Loddenkemper C, Kühl AA, Lepenies I, Lexberg MH, Westendorf K, Hradilkova K, Grün J, Hamann A, Epstein JA, Chang HD, Tokoyoda K, Radbruch A. Albrecht I, et al. Among authors: westendorf k. Eur J Immunol. 2010 Nov;40(11):2993-3006. doi: 10.1002/eji.201040936. Epub 2010 Oct 27. Eur J Immunol. 2010. PMID: 21061432 Free article.
Unbiased transcriptomes of resting human CD4⁺ CD45RO⁺ T lymphocytes.
Westendorf K, Okhrimenko A, Grün JR, Schliemann H, Chang HD, Dong J, Radbruch A. Westendorf K, et al. Eur J Immunol. 2014 Jun;44(6):1866-9. doi: 10.1002/eji.201344323. Epub 2014 Apr 16. Eur J Immunol. 2014. PMID: 24609896 Free PMC article. No abstract available.
Discrete populations of isotype-switched memory B lymphocytes are maintained in murine spleen and bone marrow.
Riedel R, Addo R, Ferreira-Gomes M, Heinz GA, Heinrich F, Kummer J, Greiff V, Schulz D, Klaeden C, Cornelis R, Menzel U, Kröger S, Stervbo U, Köhler R, Haftmann C, Kühnel S, Lehmann K, Maschmeyer P, McGrath M, Naundorf S, Hahne S, Sercan-Alp Ö, Siracusa F, Stefanowski J, Weber M, Westendorf K, Zimmermann J, Hauser AE, Reddy ST, Durek P, Chang HD, Mashreghi MF, Radbruch A. Riedel R, et al. Among authors: westendorf k. Nat Commun. 2020 May 22;11(1):2570. doi: 10.1038/s41467-020-16464-6. Nat Commun. 2020. PMID: 32444631 Free PMC article.
T-bet expression by Th cells promotes type 1 inflammation but is dispensable for colitis.
Zimmermann J, Kühl AA, Weber M, Grün JR, Löffler J, Haftmann C, Riedel R, Maschmeyer P, Lehmann K, Westendorf K, Mashreghi MF, Löhning M, Mack M, Radbruch A, Chang HD. Zimmermann J, et al. Among authors: westendorf k. Mucosal Immunol. 2016 Nov;9(6):1487-1499. doi: 10.1038/mi.2016.5. Epub 2016 Feb 17. Mucosal Immunol. 2016. PMID: 26883725 Free article.
Regulation of Fatty Acid Oxidation by Twist 1 in the Metabolic Adaptation of T Helper Lymphocytes to Chronic Inflammation.
Hradilkova K, Maschmeyer P, Westendorf K, Schliemann H, Husak O, von Stuckrad ASL, Kallinich T, Minden K, Durek P, Grün JR, Chang HD, Radbruch A. Hradilkova K, et al. Among authors: westendorf k. Arthritis Rheumatol. 2019 Oct;71(10):1756-1765. doi: 10.1002/art.40939. Epub 2019 Sep 5. Arthritis Rheumatol. 2019. PMID: 31131995 Free PMC article.
miR-148a is upregulated by Twist1 and T-bet and promotes Th1-cell survival by regulating the proapoptotic gene Bim.
Haftmann C, Stittrich AB, Zimmermann J, Fang Z, Hradilkova K, Bardua M, Westendorf K, Heinz GA, Riedel R, Siede J, Lehmann K, Weinberger EE, Zimmel D, Lauer U, Häupl T, Sieper J, Backhaus M, Neumann C, Hoffmann U, Porstner M, Chen W, Grün JR, Baumgrass R, Matz M, Löhning M, Scheffold A, Wittmann J, Chang HD, Rajewsky N, Jäck HM, Radbruch A, Mashreghi MF. Haftmann C, et al. Among authors: westendorf k. Eur J Immunol. 2015 Apr;45(4):1192-205. doi: 10.1002/eji.201444633. Epub 2015 Jan 22. Eur J Immunol. 2015. PMID: 25486906 Free PMC article.
MicroRNA-31 Reduces the Motility of Proinflammatory T Helper 1 Lymphocytes.
Bardua M, Haftmann C, Durek P, Westendorf K, Buttgereit A, Tran CL, McGrath M, Weber M, Lehmann K, Addo RK, Heinz GA, Stittrich AB, Maschmeyer P, Radbruch H, Lohoff M, Chang HD, Radbruch A, Mashreghi MF. Bardua M, et al. Among authors: westendorf k. Front Immunol. 2018 Dec 6;9:2813. doi: 10.3389/fimmu.2018.02813. eCollection 2018. Front Immunol. 2018. PMID: 30574141 Free PMC article.
27 results