Aitken JF - Search Results

1

Monodisperse 130 kDa and 260 kDa Recombinant Human Hemoglobin Polymers as Scaffolds for Protein Engineering of Hemoglobin-Based Oxygen Carriers.

Marquardt DA, Doyle MP, Davidson JS, Epp JK, Aitken JF, Lemon DD, Anthony-Cahill SJ. Marquardt DA, et al. Among authors: aitken jf. J Funct Biomater. 2012 Jan 13;3(1):61-78. doi: 10.3390/jfb3010061. J Funct Biomater. 2012. PMID: 24956516 Free PMC article.

2

Recombinant protein sequences can trigger methylation of N-terminal amino acids in Escherichia coli.

Apostol I, Aitken J, Levine J, Lippincott J, Davidson JS, Abbott-Brown D. Apostol I, et al. Protein Sci. 1995 Dec;4(12):2616-8. doi: 10.1002/pro.5560041219. Protein Sci. 1995. PMID: 8580853 Free PMC article.

3

Mechanism of NO-induced oxidation of myoglobin and hemoglobin.

Eich RF, Li T, Lemon DD, Doherty DH, Curry SR, Aitken JF, Mathews AJ, Johnson KA, Smith RD, Phillips GN Jr, Olson JS. Eich RF, et al. Among authors: aitken jf. Biochemistry. 1996 Jun 4;35(22):6976-83. doi: 10.1021/bi960442g. Biochemistry. 1996. PMID: 8679521

4

The gene encoding the phosphatidylinositol transfer protein is essential for cell growth.

Aitken JF, van Heusden GP, Temkin M, Dowhan W. Aitken JF, et al. J Biol Chem. 1990 Mar 15;265(8):4711-7. J Biol Chem. 1990. PMID: 2407740 Free article.

5

The chaperone proteins HSP70, HSP40/DnaJ and GRP78/BiP suppress misfolding and formation of β-sheet-containing aggregates by human amylin: a potential role for defective chaperone biology in Type 2 diabetes.

Chien V, Aitken JF, Zhang S, Buchanan CM, Hickey A, Brittain T, Cooper GJ, Loomes KM. Chien V, et al. Among authors: aitken jf. Biochem J. 2010 Nov 15;432(1):113-21. doi: 10.1042/BJ20100434. Biochem J. 2010. PMID: 20735358

6

Suppression by polycyclic compounds of the conversion of human amylin into insoluble amyloid.

Aitken JF, Loomes KM, Konarkowska B, Cooper GJ. Aitken JF, et al. Biochem J. 2003 Sep 15;374(Pt 3):779-84. doi: 10.1042/BJ20030422. Biochem J. 2003. PMID: 12812521 Free PMC article.

7

The aggregation potential of human amylin determines its cytotoxicity towards islet beta-cells.

Konarkowska B, Aitken JF, Kistler J, Zhang S, Cooper GJ. Konarkowska B, et al. Among authors: aitken jf. FEBS J. 2006 Aug;273(15):3614-24. doi: 10.1111/j.1742-4658.2006.05367.x. FEBS J. 2006. PMID: 16884500 Free article.

8

Tetracycline treatment retards the onset and slows the progression of diabetes in human amylin/islet amyloid polypeptide transgenic mice.

Aitken JF, Loomes KM, Scott DW, Reddy S, Phillips AR, Prijic G, Fernando C, Zhang S, Broadhurst R, L'Huillier P, Cooper GJ. Aitken JF, et al. Diabetes. 2010 Jan;59(1):161-71. doi: 10.2337/db09-0548. Epub 2009 Sep 30. Diabetes. 2010. PMID: 19794060 Free PMC article.

9

Rutin suppresses human-amylin/hIAPP misfolding and oligomer formation in-vitro, and ameliorates diabetes and its impacts in human-amylin/hIAPP transgenic mice.

Aitken JF, Loomes KM, Riba-Garcia I, Unwin RD, Prijic G, Phillips AS, Phillips ARJ, Wu D, Poppitt SD, Ding K, Barran PE, Dowsey AW, Cooper GJS. Aitken JF, et al. Biochem Biophys Res Commun. 2017 Jan 22;482(4):625-631. doi: 10.1016/j.bbrc.2016.11.083. Epub 2016 Nov 16. Biochem Biophys Res Commun. 2017. PMID: 27865831

10

Is type 2 diabetes an amyloidosis and does it really matter (to patients)?

Cooper GJ, Aitken JF, Zhang S. Cooper GJ, et al. Among authors: aitken jf. Diabetologia. 2010 Jun;53(6):1011-6. doi: 10.1007/s00125-010-1715-y. Epub 2010 Mar 13. Diabetologia. 2010. PMID: 20229094 Free article. No abstract available.

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