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The TPM3-NTRK1 rearrangement is a recurring event in colorectal carcinoma and is associated with tumor sensitivity to TRKA kinase inhibition.
Ardini E, Bosotti R, Borgia AL, De Ponti C, Somaschini A, Cammarota R, Amboldi N, Raddrizzani L, Milani A, Magnaghi P, Ballinari D, Casero D, Gasparri F, Banfi P, Avanzi N, Saccardo MB, Alzani R, Bandiera T, Felder E, Donati D, Pesenti E, Sartore-Bianchi A, Gambacorta M, Pierotti MA, Siena S, Veronese S, Galvani A, Isacchi A. Ardini E, et al. Among authors: pierotti ma. Mol Oncol. 2014 Dec;8(8):1495-507. doi: 10.1016/j.molonc.2014.06.001. Epub 2014 Jun 12. Mol Oncol. 2014. PMID: 24962792 Free PMC article.
RET inhibition: implications in cancer therapy.
Borrello MG, Ardini E, Locati LD, Greco A, Licitra L, Pierotti MA. Borrello MG, et al. Among authors: pierotti ma. Expert Opin Ther Targets. 2013 Apr;17(4):403-19. doi: 10.1517/14728222.2013.758715. Epub 2013 Mar 6. Expert Opin Ther Targets. 2013. PMID: 23461584 Review.
Rearrangements of NTRK1 gene in papillary thyroid carcinoma.
Greco A, Miranda C, Pierotti MA. Greco A, et al. Among authors: pierotti ma. Mol Cell Endocrinol. 2010 May 28;321(1):44-9. doi: 10.1016/j.mce.2009.10.009. Epub 2009 Oct 31. Mol Cell Endocrinol. 2010. PMID: 19883730 Review.
Targeted therapies: the rare cancer paradigm.
Pierotti MA, Negri T, Tamborini E, Perrone F, Pricl S, Pilotti S. Pierotti MA, et al. Mol Oncol. 2010 Feb;4(1):19-37. doi: 10.1016/j.molonc.2009.10.003. Epub 2009 Oct 28. Mol Oncol. 2010. PMID: 19913465 Free PMC article. Review.
Are two better than one? A novel double-mutant KIT in GIST that responds to Imatinib.
Conca E, Miranda C, Dal Col V, Fumagalli E, Pelosi G, Mazzoni M, Fermeglia M, Laurini E, Pierotti MA, Pilotti S, Greco A, Pricl S, Tamborini E. Conca E, et al. Among authors: pierotti ma. Mol Oncol. 2013 Aug;7(4):756-62. doi: 10.1016/j.molonc.2013.02.019. Epub 2013 Mar 21. Mol Oncol. 2013. PMID: 23567324 Free PMC article.
471 results