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GABA from reactive astrocytes impairs memory in mouse models of Alzheimer's disease.
Jo S, Yarishkin O, Hwang YJ, Chun YE, Park M, Woo DH, Bae JY, Kim T, Lee J, Chun H, Park HJ, Lee DY, Hong J, Kim HY, Oh SJ, Park SJ, Lee H, Yoon BE, Kim Y, Jeong Y, Shim I, Bae YC, Cho J, Kowall NW, Ryu H, Hwang E, Kim D, Lee CJ. Jo S, et al. Among authors: lee dy, lee cj, lee h, lee j. Nat Med. 2014 Aug;20(8):886-96. doi: 10.1038/nm.3639. Epub 2014 Jun 29. Nat Med. 2014. PMID: 24973918 Free PMC article.
Cell subtype-specific effects of genetic variation in the Alzheimer's disease brain.
Fujita M, Gao Z, Zeng L, McCabe C, White CC, Ng B, Green GS, Rozenblatt-Rosen O, Phillips D, Amir-Zilberstein L, Lee H, Pearse RV 2nd, Khan A, Vardarajan BN, Kiryluk K, Ye CJ, Klein HU, Wang G, Regev A, Habib N, Schneider JA, Wang Y, Young-Pearse T, Mostafavi S, Bennett DA, Menon V, De Jager PL. Fujita M, et al. Among authors: lee h. Nat Genet. 2024 Apr;56(4):605-614. doi: 10.1038/s41588-024-01685-y. Epub 2024 Mar 21. Nat Genet. 2024. PMID: 38514782
INPP5D regulates inflammasome activation in human microglia.
Chou V, Pearse RV 2nd, Aylward AJ, Ashour N, Taga M, Terzioglu G, Fujita M, Fancher SB, Sigalov A, Benoit CR, Lee H, Lam M, Seyfried NT, Bennett DA, De Jager PL, Menon V, Young-Pearse TL. Chou V, et al. Among authors: lee h. Nat Commun. 2023 Nov 29;14(1):7552. doi: 10.1038/s41467-023-42819-w. Nat Commun. 2023. PMID: 38016942 Free PMC article.
VLDLR and ApoER2 are receptors for multiple alphaviruses.
Clark LE, Clark SA, Lin C, Liu J, Coscia A, Nabel KG, Yang P, Neel DV, Lee H, Brusic V, Stryapunina I, Plante KS, Ahmed AA, Catteruccia F, Young-Pearse TL, Chiu IM, Llopis PM, Weaver SC, Abraham J. Clark LE, et al. Among authors: lee h. Nature. 2022 Feb;602(7897):475-480. doi: 10.1038/s41586-021-04326-0. Epub 2021 Dec 20. Nature. 2022. PMID: 34929721 Free PMC article.
Stem cell-derived neurons reflect features of protein networks, neuropathology, and cognitive outcome of their aged human donors.
Lagomarsino VN, Pearse RV 2nd, Liu L, Hsieh YC, Fernandez MA, Vinton EA, Paull D, Felsky D, Tasaki S, Gaiteri C, Vardarajan B, Lee H, Muratore CR, Benoit CR, Chou V, Fancher SB, He A, Merchant JP, Duong DM, Martinez H, Zhou M, Bah F, Vicent MA, Stricker JMS, Xu J, Dammer EB, Levey AI, Chibnik LB, Menon V, Seyfried NT, De Jager PL, Noggle S, Selkoe DJ, Bennett DA, Young-Pearse TL. Lagomarsino VN, et al. Among authors: lee h. Neuron. 2021 Nov 3;109(21):3402-3420.e9. doi: 10.1016/j.neuron.2021.08.003. Epub 2021 Sep 1. Neuron. 2021. PMID: 34473944 Free PMC article.
Cell-type-specific regulation of APOE and CLU levels in human neurons by the Alzheimer's disease risk gene SORL1.
Lee H, Aylward AJ, Pearse RV 2nd, Lish AM, Hsieh YC, Augur ZM, Benoit CR, Chou V, Knupp A, Pan C, Goberdhan S, Duong DM, Seyfried NT, Bennett DA, Taga MF, Huynh K, Arnold M, Meikle PJ, De Jager PL, Menon V, Young JE, Young-Pearse TL. Lee H, et al. Cell Rep. 2023 Aug 29;42(8):112994. doi: 10.1016/j.celrep.2023.112994. Epub 2023 Aug 22. Cell Rep. 2023. PMID: 37611586 Free PMC article.
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