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The structural basis for autonomous dimerization of the pre-T-cell antigen receptor.
Pang SS, Berry R, Chen Z, Kjer-Nielsen L, Perugini MA, King GF, Wang C, Chew SH, La Gruta NL, Williams NK, Beddoe T, Tiganis T, Cowieson NP, Godfrey DI, Purcell AW, Wilce MC, McCluskey J, Rossjohn J. Pang SS, et al. Among authors: tiganis t. Nature. 2010 Oct 14;467(7317):844-8. doi: 10.1038/nature09448. Nature. 2010. PMID: 20944746
Elevated hypothalamic TCPTP in obesity contributes to cellular leptin resistance.
Loh K, Fukushima A, Zhang X, Galic S, Briggs D, Enriori PJ, Simonds S, Wiede F, Reichenbach A, Hauser C, Sims NA, Bence KK, Zhang S, Zhang ZY, Kahn BB, Neel BG, Andrews ZB, Cowley MA, Tiganis T. Loh K, et al. Among authors: tiganis t. Cell Metab. 2011 Nov 2;14(5):684-99. doi: 10.1016/j.cmet.2011.09.011. Epub 2011 Oct 13. Cell Metab. 2011. PMID: 22000926 Free PMC article.
TCPTP regulates SFK and STAT3 signaling and is lost in triple-negative breast cancers.
Shields BJ, Wiede F, Gurzov EN, Wee K, Hauser C, Zhu HJ, Molloy TJ, O'Toole SA, Daly RJ, Sutherland RL, Mitchell CA, McLean CA, Tiganis T. Shields BJ, et al. Among authors: tiganis t. Mol Cell Biol. 2013 Feb;33(3):557-70. doi: 10.1128/MCB.01016-12. Epub 2012 Nov 19. Mol Cell Biol. 2013. PMID: 23166300 Free PMC article.
Characterization of PTPN2 and its use as a biomarker.
Bussières-Marmen S, Hutchins AP, Schirbel A, Rebert N, Tiganis T, Fiocchi C, Miranda-Saavedra D, Tremblay ML. Bussières-Marmen S, et al. Among authors: tiganis t. Methods. 2014 Jan 15;65(2):239-46. doi: 10.1016/j.ymeth.2013.08.020. Epub 2013 Aug 30. Methods. 2014. PMID: 23994241
123 results