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Insulin receptor substrates are essential for the bioenergetic and hypertrophic response of the heart to exercise training.
Riehle C, Wende AR, Zhu Y, Oliveira KJ, Pereira RO, Jaishy BP, Bevins J, Valdez S, Noh J, Kim BJ, Moreira AB, Weatherford ET, Manivel R, Rawlings TA, Rech M, White MF, Abel ED. Riehle C, et al. Among authors: wende ar. Mol Cell Biol. 2014 Sep 15;34(18):3450-60. doi: 10.1128/MCB.00426-14. Epub 2014 Jul 7. Mol Cell Biol. 2014. PMID: 25002528 Free PMC article.
PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis.
Leone TC, Lehman JJ, Finck BN, Schaeffer PJ, Wende AR, Boudina S, Courtois M, Wozniak DF, Sambandam N, Bernal-Mizrachi C, Chen Z, Holloszy JO, Medeiros DM, Schmidt RE, Saffitz JE, Abel ED, Semenkovich CF, Kelly DP. Leone TC, et al. Among authors: wende ar. PLoS Biol. 2005 Apr;3(4):e101. doi: 10.1371/journal.pbio.0030101. Epub 2005 Mar 15. PLoS Biol. 2005. PMID: 15760270 Free PMC article.
A conserved role for phosphatidylinositol 3-kinase but not Akt signaling in mitochondrial adaptations that accompany physiological cardiac hypertrophy.
O'Neill BT, Kim J, Wende AR, Theobald HA, Tuinei J, Buchanan J, Guo A, Zaha VG, Davis DK, Schell JC, Boudina S, Wayment B, Litwin SE, Shioi T, Izumo S, Birnbaum MJ, Abel ED. O'Neill BT, et al. Among authors: wende ar. Cell Metab. 2007 Oct;6(4):294-306. doi: 10.1016/j.cmet.2007.09.001. Cell Metab. 2007. PMID: 17908558 Free PMC article.
Lipotoxicity in the heart.
Wende AR, Abel ED. Wende AR, et al. Biochim Biophys Acta. 2010 Mar;1801(3):311-9. doi: 10.1016/j.bbalip.2009.09.023. Epub 2009 Oct 8. Biochim Biophys Acta. 2010. PMID: 19818871 Free PMC article. Review.
Aberrant water homeostasis detected by stable isotope analysis.
O'Grady SP, Wende AR, Remien CH, Valenzuela LO, Enright LE, Chesson LA, Abel ED, Cerling TE, Ehleringer JR. O'Grady SP, et al. Among authors: wende ar. PLoS One. 2010 Jul 21;5(7):e11699. doi: 10.1371/journal.pone.0011699. PLoS One. 2010. PMID: 20657736 Free PMC article.
93 results