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Hedgehog controls hepatic stellate cell fate by regulating metabolism.
Chen Y, Choi SS, Michelotti GA, Chan IS, Swiderska-Syn M, Karaca GF, Xie G, Moylan CA, Garibaldi F, Premont R, Suliman HB, Piantadosi CA, Diehl AM. Chen Y, et al. Gastroenterology. 2012 Nov;143(5):1319-1329.e11. doi: 10.1053/j.gastro.2012.07.115. Epub 2012 Aug 8. Gastroenterology. 2012. PMID: 22885334 Free PMC article.
Paracrine Hedgehog signaling drives metabolic changes in hepatocellular carcinoma.
Chan IS, Guy CD, Chen Y, Lu J, Swiderska-Syn M, Michelotti GA, Karaca G, Xie G, Krüger L, Syn WK, Anderson BR, Pereira TA, Choi SS, Baldwin AS, Diehl AM. Chan IS, et al. Cancer Res. 2012 Dec 15;72(24):6344-50. doi: 10.1158/0008-5472.CAN-12-1068. Epub 2012 Oct 12. Cancer Res. 2012. PMID: 23066040 Free PMC article.
Hedgehog pathway and pediatric nonalcoholic fatty liver disease.
Swiderska-Syn M, Suzuki A, Guy CD, Schwimmer JB, Abdelmalek MF, Lavine JE, Diehl AM. Swiderska-Syn M, et al. Hepatology. 2013 May;57(5):1814-25. doi: 10.1002/hep.26230. Epub 2013 Apr 1. Hepatology. 2013. PMID: 23300059 Free PMC article.
Alcohol activates the hedgehog pathway and induces related procarcinogenic processes in the alcohol-preferring rat model of hepatocarcinogenesis.
Chan IS, Guy CD, Machado MV, Wank A, Kadiyala V, Michelotti G, Choi S, Swiderska-Syn M, Karaca G, Pereira TA, Yip-Schneider MT, Max Schmidt C, Diehl AM. Chan IS, et al. Alcohol Clin Exp Res. 2014 Mar;38(3):787-800. doi: 10.1111/acer.12279. Epub 2013 Oct 24. Alcohol Clin Exp Res. 2014. PMID: 24164383 Free PMC article.
Osteopontin neutralisation abrogates the liver progenitor cell response and fibrogenesis in mice.
Coombes JD, Swiderska-Syn M, Dollé L, Reid D, Eksteen B, Claridge L, Briones-Orta MA, Shetty S, Oo YH, Riva A, Chokshi S, Papa S, Mi Z, Kuo PC, Williams R, Canbay A, Adams DH, Diehl AM, van Grunsven LA, Choi SS, Syn WK. Coombes JD, et al. Gut. 2015 Jul;64(7):1120-31. doi: 10.1136/gutjnl-2013-306484. Epub 2014 Jun 5. Gut. 2015. PMID: 24902765 Free PMC article.
29 results