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Manganese homeostasis in the nervous system.
Chen P, Chakraborty S, Mukhopadhyay S, Lee E, Paoliello MM, Bowman AB, Aschner M. Chen P, et al. Among authors: bowman ab. J Neurochem. 2015 Aug;134(4):601-10. doi: 10.1111/jnc.13170. Epub 2015 Jun 16. J Neurochem. 2015. PMID: 25982296 Free PMC article. Review.
Allosteric activation of M4 muscarinic receptors improve behavioral and physiological alterations in early symptomatic YAC128 mice.
Pancani T, Foster DJ, Moehle MS, Bichell TJ, Bradley E, Bridges TM, Klar R, Poslusney M, Rook JM, Daniels JS, Niswender CM, Jones CK, Wood MR, Bowman AB, Lindsley CW, Xiang Z, Conn PJ. Pancani T, et al. Among authors: bowman ab. Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):14078-83. doi: 10.1073/pnas.1512812112. Epub 2015 Oct 27. Proc Natl Acad Sci U S A. 2015. PMID: 26508634 Free PMC article.
The effects of manganese overexposure on brain health.
Miah MR, Ijomone OM, Okoh COA, Ijomone OK, Akingbade GT, Ke T, Krum B, da Cunha Martins A Jr, Akinyemi A, Aranoff N, Antunes Soares FA, Bowman AB, Aschner M. Miah MR, et al. Among authors: bowman ab. Neurochem Int. 2020 May;135:104688. doi: 10.1016/j.neuint.2020.104688. Epub 2020 Jan 20. Neurochem Int. 2020. PMID: 31972215 Free PMC article. Review.
Defective Mitochondrial Dynamics Underlie Manganese-Induced Neurotoxicity.
Morcillo P, Cordero H, Ijomone OM, Ayodele A, Bornhorst J, Gunther L, Macaluso FP, Bowman AB, Aschner M. Morcillo P, et al. Among authors: bowman ab. Mol Neurobiol. 2021 Jul;58(7):3270-3289. doi: 10.1007/s12035-021-02341-w. Epub 2021 Mar 5. Mol Neurobiol. 2021. PMID: 33666854 Free PMC article.
Treatment with THI, an inhibitor of sphingosine-1-phosphate lyase, modulates glycosphingolipid metabolism and results therapeutically effective in experimental models of Huntington's disease.
Pepe G, Capocci L, Marracino F, Realini N, Lenzi P, Martinello K, Bovier TF, Bichell TJ, Scarselli P, Di Cicco C, Bowman AB, Digilio FA, Fucile S, Fornai F, Armirotti A, Parlato R, Di Pardo A, Maglione V. Pepe G, et al. Among authors: bowman ab. Mol Ther. 2023 Jan 4;31(1):282-299. doi: 10.1016/j.ymthe.2022.09.004. Epub 2022 Sep 16. Mol Ther. 2023. PMID: 36116006 Free PMC article.
152 results