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High-fat-diet-mediated dysbiosis promotes intestinal carcinogenesis independently of obesity.
Schulz MD, Atay C, Heringer J, Romrig FK, Schwitalla S, Aydin B, Ziegler PK, Varga J, Reindl W, Pommerenke C, Salinas-Riester G, Böck A, Alpert C, Blaut M, Polson SC, Brandl L, Kirchner T, Greten FR, Polson SW, Arkan MC. Schulz MD, et al. Among authors: greten fr. Nature. 2014 Oct 23;514(7523):508-12. doi: 10.1038/nature13398. Epub 2014 Aug 31. Nature. 2014. PMID: 25174708 Free PMC article.
IKK-beta links inflammation to obesity-induced insulin resistance.
Arkan MC, Hevener AL, Greten FR, Maeda S, Li ZW, Long JM, Wynshaw-Boris A, Poli G, Olefsky J, Karin M. Arkan MC, et al. Among authors: greten fr. Nat Med. 2005 Feb;11(2):191-8. doi: 10.1038/nm1185. Epub 2005 Jan 30. Nat Med. 2005. PMID: 15685170
Opposing functions of IKKbeta during acute and chronic intestinal inflammation.
Eckmann L, Nebelsiek T, Fingerle AA, Dann SM, Mages J, Lang R, Robine S, Kagnoff MF, Schmid RM, Karin M, Arkan MC, Greten FR. Eckmann L, et al. Among authors: greten fr. Proc Natl Acad Sci U S A. 2008 Sep 30;105(39):15058-63. doi: 10.1073/pnas.0808216105. Epub 2008 Sep 24. Proc Natl Acad Sci U S A. 2008. PMID: 18815378 Free PMC article.
gp130-mediated Stat3 activation in enterocytes regulates cell survival and cell-cycle progression during colitis-associated tumorigenesis.
Bollrath J, Phesse TJ, von Burstin VA, Putoczki T, Bennecke M, Bateman T, Nebelsiek T, Lundgren-May T, Canli O, Schwitalla S, Matthews V, Schmid RM, Kirchner T, Arkan MC, Ernst M, Greten FR. Bollrath J, et al. Among authors: greten fr. Cancer Cell. 2009 Feb 3;15(2):91-102. doi: 10.1016/j.ccr.2009.01.002. Cancer Cell. 2009. PMID: 19185844 Free article.
Inflammation and mitochondrial fatty acid beta-oxidation link obesity to early tumor promotion.
Khasawneh J, Schulz MD, Walch A, Rozman J, Hrabe de Angelis M, Klingenspor M, Buck A, Schwaiger M, Saur D, Schmid RM, Klöppel G, Sipos B, Greten FR, Arkan MC. Khasawneh J, et al. Among authors: greten fr. Proc Natl Acad Sci U S A. 2009 Mar 3;106(9):3354-9. doi: 10.1073/pnas.0802864106. Epub 2009 Feb 10. Proc Natl Acad Sci U S A. 2009. PMID: 19208810 Free PMC article.
IKK- and NF-κB-mediated functions in carcinogenesis.
Arkan MC, Greten FR. Arkan MC, et al. Among authors: greten fr. Curr Top Microbiol Immunol. 2011;349:159-69. doi: 10.1007/82_2010_97. Curr Top Microbiol Immunol. 2011. PMID: 20845109 Review.
123 results