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Signaling-specific inhibition of the CB1 receptor for cannabis use disorder: phase 1 and phase 2a randomized trials.
Haney M, Vallée M, Fabre S, Collins Reed S, Zanese M, Campistron G, Arout CA, Foltin RW, Cooper ZD, Kearney-Ramos T, Metna M, Justinova Z, Schindler C, Hebert-Chatelain E, Bellocchio L, Cathala A, Bari A, Serrat R, Finlay DB, Caraci F, Redon B, Martín-García E, Busquets-Garcia A, Matias I, Levin FR, Felpin FX, Simon N, Cota D, Spampinato U, Maldonado R, Shaham Y, Glass M, Thomsen LL, Mengel H, Marsicano G, Monlezun S, Revest JM, Piazza PV. Haney M, et al. Among authors: cota d. Nat Med. 2023 Jun;29(6):1487-1499. doi: 10.1038/s41591-023-02381-w. Epub 2023 Jun 8. Nat Med. 2023. PMID: 37291212 Free PMC article. Clinical Trial.
CB(1) signaling in forebrain and sympathetic neurons is a key determinant of endocannabinoid actions on energy balance.
Quarta C, Bellocchio L, Mancini G, Mazza R, Cervino C, Braulke LJ, Fekete C, Latorre R, Nanni C, Bucci M, Clemens LE, Heldmaier G, Watanabe M, Leste-Lassere T, Maitre M, Tedesco L, Fanelli F, Reuss S, Klaus S, Srivastava RK, Monory K, Valerio A, Grandis A, De Giorgio R, Pasquali R, Nisoli E, Cota D, Lutz B, Marsicano G, Pagotto U. Quarta C, et al. Among authors: cota d. Cell Metab. 2010 Apr 7;11(4):273-85. doi: 10.1016/j.cmet.2010.02.015. Cell Metab. 2010. PMID: 20374960 Free article.
mTORC1 signaling in energy balance and metabolic disease.
Catania C, Binder E, Cota D. Catania C, et al. Among authors: cota d. Int J Obes (Lond). 2011 Jun;35(6):751-61. doi: 10.1038/ijo.2010.208. Epub 2010 Sep 28. Int J Obes (Lond). 2011. PMID: 20877289 Review.
Leucine supplementation protects from insulin resistance by regulating adiposity levels.
Binder E, Bermúdez-Silva FJ, André C, Elie M, Romero-Zerbo SY, Leste-Lasserre T, Belluomo I, Duchampt A, Clark S, Aubert A, Mezzullo M, Fanelli F, Pagotto U, Layé S, Mithieux G, Cota D. Binder E, et al. Among authors: cota d. PLoS One. 2013 Sep 25;8(9):e74705. doi: 10.1371/journal.pone.0074705. eCollection 2013. PLoS One. 2013. PMID: 24086364 Free PMC article.
CB1 cannabinoid receptor in SF1-expressing neurons of the ventromedial hypothalamus determines metabolic responses to diet and leptin.
Cardinal P, André C, Quarta C, Bellocchio L, Clark S, Elie M, Leste-Lasserre T, Maitre M, Gonzales D, Cannich A, Pagotto U, Marsicano G, Cota D. Cardinal P, et al. Among authors: cota d. Mol Metab. 2014 Aug 1;3(7):705-16. doi: 10.1016/j.molmet.2014.07.004. eCollection 2014 Oct. Mol Metab. 2014. PMID: 25352999 Free PMC article.
111 results