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Impact of site-specific phosphorylation of protein kinase A sites Ser23 and Ser24 of cardiac troponin I in human cardiomyocytes.
Wijnker PJ, Foster DB, Tsao AL, Frazier AH, dos Remedios CG, Murphy AM, Stienen GJ, van der Velden J. Wijnker PJ, et al. Among authors: stienen gj. Am J Physiol Heart Circ Physiol. 2013 Jan 15;304(2):H260-8. doi: 10.1152/ajpheart.00498.2012. Epub 2012 Nov 9. Am J Physiol Heart Circ Physiol. 2013. PMID: 23144315 Free PMC article.
Length-dependent activation is modulated by cardiac troponin I bisphosphorylation at Ser23 and Ser24 but not by Thr143 phosphorylation.
Wijnker PJ, Sequeira V, Foster DB, Li Y, Dos Remedios CG, Murphy AM, Stienen GJ, van der Velden J. Wijnker PJ, et al. Among authors: stienen gj. Am J Physiol Heart Circ Physiol. 2014 Apr 15;306(8):H1171-81. doi: 10.1152/ajpheart.00580.2013. Epub 2014 Feb 28. Am J Physiol Heart Circ Physiol. 2014. PMID: 24585778 Free PMC article.
A novel phosphorylation site, Serine 199, in the C-terminus of cardiac troponin I regulates calcium sensitivity and susceptibility to calpain-induced proteolysis.
Wijnker PJ, Li Y, Zhang P, Foster DB, dos Remedios C, Van Eyk JE, Stienen GJ, Murphy AM, van der Velden J. Wijnker PJ, et al. Among authors: stienen gj. J Mol Cell Cardiol. 2015 May;82:93-103. doi: 10.1016/j.yjmcc.2015.03.006. Epub 2015 Mar 11. J Mol Cell Cardiol. 2015. PMID: 25771144 Free PMC article.
ENerGetIcs in hypertrophic cardiomyopathy: traNslation between MRI, PET and cardiac myofilament function (ENGINE study).
Güçlü A, Germans T, Witjas-Paalberends ER, Stienen GJ, Brouwer WP, Harms HJ, Marcus JT, Vonk AB, Stooker W, Yilmaz A, Klein P, Ten Berg JM, Kluin J, Asselbergs FW, Lammertsma AA, Knaapen P, van Rossum AC, van der Velden J. Güçlü A, et al. Among authors: stienen gj. Neth Heart J. 2013 Dec;21(12):567-71. doi: 10.1007/s12471-013-0478-8. Neth Heart J. 2013. PMID: 24114686 Free PMC article.
Impaired diastolic function after exchange of endogenous troponin I with C-terminal truncated troponin I in human cardiac muscle.
Narolska NA, Piroddi N, Belus A, Boontje NM, Scellini B, Deppermann S, Zaremba R, Musters RJ, dos Remedios C, Jaquet K, Foster DB, Murphy AM, van Eyk JE, Tesi C, Poggesi C, van der Velden J, Stienen GJ. Narolska NA, et al. Among authors: stienen gj. Circ Res. 2006 Oct 27;99(9):1012-20. doi: 10.1161/01.RES.0000248753.30340.af. Epub 2006 Oct 5. Circ Res. 2006. PMID: 17023673
178 results