Butters TD - Search Results

1

N- and C-alkylation of seven-membered iminosugars generates potent glucocerebrosidase inhibitors and F508del-CFTR correctors.

Désiré J, Mondon M, Fontelle N, Nakagawa S, Hirokami Y, Adachi I, Iwaki R, Fleet GW, Alonzi DS, Twigg G, Butters TD, Bertrand J, Cendret V, Becq F, Norez C, Marrot J, Kato A, Blériot Y. Désiré J, et al. Among authors: butters td. Org Biomol Chem. 2014 Nov 28;12(44):8977-96. doi: 10.1039/c4ob00325j. Org Biomol Chem. 2014. PMID: 25277226

2

Selection of the biological activity of DNJ neoglycoconjugates through click length variation of the side chain.

Ardes-Guisot N, Alonzi DS, Reinkensmeier G, Butters TD, Norez C, Becq F, Shimada Y, Nakagawa S, Kato A, Blériot Y, Sollogoub M, Vauzeilles B. Ardes-Guisot N, et al. Among authors: butters td. Org Biomol Chem. 2011 Aug 7;9(15):5373-88. doi: 10.1039/c1ob05119a. Epub 2011 Apr 21. Org Biomol Chem. 2011. PMID: 21512716

3

New synthetic seven-membered 1-azasugars displaying potent inhibition towards glycosidases and glucosylceramide transferase.

Li H, Liu T, Zhang Y, Favre S, Bello C, Vogel P, Butters TD, Oikonomakos NG, Marrot J, Blériot Y. Li H, et al. Among authors: butters td. Chembiochem. 2008 Jan 25;9(2):253-60. doi: 10.1002/cbic.200700496. Chembiochem. 2008. PMID: 18188862

4

Towards a stable noeuromycin analog with a D-manno configuration: synthesis and glycosidase inhibition of D-manno-like tri- and tetrahydroxylated azepanes.

Deschamp J, Mondon M, Nakagawa S, Kato A, Alonzi DS, Butters TD, Zhang Y, Sollogoub M, Blériot Y. Deschamp J, et al. Among authors: butters td. Bioorg Med Chem. 2012 Jan 15;20(2):641-9. doi: 10.1016/j.bmc.2010.09.053. Epub 2010 Oct 1. Bioorg Med Chem. 2012. PMID: 20971647

5

C-branched iminosugars: α-glucosidase inhibition by enantiomers of isoDMDP, isoDGDP, and isoDAB-L-isoDMDP compared to miglitol and miglustat.

Jenkinson SF, Best D, Saville AW, Mui J, Martínez RF, Nakagawa S, Kunimatsu T, Alonzi DS, Butters TD, Norez C, Becq F, Blériot Y, Wilson FX, Weymouth-Wilson AC, Kato A, Fleet GW. Jenkinson SF, et al. Among authors: butters td. J Org Chem. 2013 Aug 2;78(15):7380-97. doi: 10.1021/jo4005487. Epub 2013 Jun 5. J Org Chem. 2013. PMID: 23688199

6

Rescue of functional CFTR channels in cystic fibrosis: a dramatic multivalent effect using iminosugar cluster-based correctors.

Compain P, Decroocq C, Joosten A, de Sousa J, Rodríguez-Lucena D, Butters TD, Bertrand J, Clément R, Boinot C, Becq F, Norez C. Compain P, et al. Among authors: butters td. Chembiochem. 2013 Oct 11;14(15):2050-8. doi: 10.1002/cbic.201300312. Epub 2013 Sep 13. Chembiochem. 2013. PMID: 24038832

7

Synthesis of the enantiomers of XYLNAc and LYXNAc: comparison of β-N-acetylhexosaminidase inhibition by the 8 stereoisomers of 2-N-acetylamino-1,2,4-trideoxy-1,4-iminopentitols.

Crabtree EV, Martínez RF, Nakagawa S, Adachi I, Butters TD, Kato A, Fleet GW, Glawar AF. Crabtree EV, et al. Among authors: butters td. Org Biomol Chem. 2014 Jun 21;12(23):3932-43. doi: 10.1039/c4ob00097h. Org Biomol Chem. 2014. PMID: 24802185

8

Looking glass inhibitors: efficient synthesis and biological evaluation of D-deoxyfuconojirimycin.

Blériot Y, Gretzke D, Krülle TM, Butters TD, Dwek RA, Nash RJ, Asano N, Fleet GW. Blériot Y, et al. Among authors: butters td. Carbohydr Res. 2005 Dec 30;340(18):2713-8. doi: 10.1016/j.carres.2005.10.002. Epub 2005 Nov 4. Carbohydr Res. 2005. PMID: 16274755

9

Design and synthesis of acetamido tri- and tetra-hydroxyazepanes: potent and selective beta-N-acetylhexosaminidase inhibitors.

Li H, Marcelo F, Bello C, Vogel P, Butters TD, Rauter AP, Zhang Y, Sollogoub M, Blériot Y. Li H, et al. Among authors: butters td. Bioorg Med Chem. 2009 Aug 1;17(15):5598-604. doi: 10.1016/j.bmc.2009.06.022. Epub 2009 Jun 17. Bioorg Med Chem. 2009. PMID: 19592259

10

Therapeutic targets for inhibitors of glycosylation.

Alonzi DS, Butters TD. Alonzi DS, et al. Among authors: butters td. Chimia (Aarau). 2011;65(1-2):35-9. doi: 10.2533/chimia.2011.35. Chimia (Aarau). 2011. PMID: 21469442 Free article. Review.

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