Michels PA - Search Results

1

Molecular basis for the reverse reaction of African human trypanosomes glycerol kinase.

Balogun EO, Inaoka DK, Shiba T, Kido Y, Tsuge C, Nara T, Aoki T, Honma T, Tanaka A, Inoue M, Matsuoka S, Michels PA, Kita K, Harada S. Balogun EO, et al. Among authors: michels pa. Mol Microbiol. 2014 Dec;94(6):1315-29. doi: 10.1111/mmi.12831. Epub 2014 Nov 4. Mol Microbiol. 2014. PMID: 25315291 Free article.

2

Overproduction, purification, crystallization and preliminary X-ray diffraction analysis of Trypanosoma brucei gambiense glycerol kinase.

Balogun EO, Inaoka DK, Kido Y, Shiba T, Nara T, Aoki T, Honma T, Tanaka A, Inoue M, Matsuoka S, Michels PA, Harada S, Kita K. Balogun EO, et al. Among authors: michels pa. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Mar 1;66(Pt 3):304-8. doi: 10.1107/S1744309110000369. Epub 2010 Feb 24. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010. PMID: 20208167 Free PMC article.

3

Biochemical characterization of highly active Trypanosoma brucei gambiense glycerol kinase, a promising drug target.

Balogun EO, Inaoka DK, Shiba T, Kido Y, Nara T, Aoki T, Honma T, Tanaka A, Inoue M, Matsuoka S, Michels PA, Harada S, Kita K. Balogun EO, et al. Among authors: michels pa. J Biochem. 2013 Jul;154(1):77-84. doi: 10.1093/jb/mvt037. Epub 2013 Apr 25. J Biochem. 2013. PMID: 23620597

4

Glycerol kinase of African trypanosomes possesses an intrinsic phosphatase activity.

Balogun EO, Inaoka DK, Shiba T, Tokuoka SM, Tokumasu F, Sakamoto K, Kido Y, Michels PAM, Watanabe YI, Harada S, Kita K. Balogun EO, et al. Biochim Biophys Acta Gen Subj. 2017 Nov;1861(11 Pt A):2830-2842. doi: 10.1016/j.bbagen.2017.07.028. Epub 2017 Aug 2. Biochim Biophys Acta Gen Subj. 2017. PMID: 28778484

5

Discovery of trypanocidal coumarins with dual inhibition of both the glycerol kinase and alternative oxidase of Trypanosoma brucei brucei.

Balogun EO, Inaoka DK, Shiba T, Tsuge C, May B, Sato T, Kido Y, Nara T, Aoki T, Honma T, Tanaka A, Inoue M, Matsuoka S, Michels PAM, Watanabe YI, Moore AL, Harada S, Kita K. Balogun EO, et al. FASEB J. 2019 Nov;33(11):13002-13013. doi: 10.1096/fj.201901342R. Epub 2019 Sep 16. FASEB J. 2019. PMID: 31525300

6

The structure of pyruvate kinase from Leishmania mexicana reveals details of the allosteric transition and unusual effector specificity.

Rigden DJ, Phillips SE, Michels PA, Fothergill-Gilmore LA. Rigden DJ, et al. Among authors: michels pa. J Mol Biol. 1999 Aug 20;291(3):615-35. doi: 10.1006/jmbi.1999.2918. J Mol Biol. 1999. PMID: 10448041

7

The crystal structure of ATP-bound phosphofructokinase from Trypanosoma brucei reveals conformational transitions different from those of other phosphofructokinases.

McNae IW, Martinez-Oyanedel J, Keillor JW, Michels PA, Fothergill-Gilmore LA, Walkinshaw MD. McNae IW, et al. Among authors: michels pa. J Mol Biol. 2009 Feb 6;385(5):1519-33. doi: 10.1016/j.jmb.2008.11.047. Epub 2008 Dec 3. J Mol Biol. 2009. PMID: 19084537

8

Leishmania mexicana glycerol-3-phosphate dehydrogenase showed conformational changes upon binding a bi-substrate adduct.

Choe J, Guerra D, Michels PA, Hol WG. Choe J, et al. Among authors: michels pa. J Mol Biol. 2003 May 30;329(2):335-49. doi: 10.1016/s0022-2836(03)00421-2. J Mol Biol. 2003. PMID: 12758080

9

Structural and kinetic characterization of Trypanosoma congolense pyruvate kinase.

Pinto Torres JE, Yuan M, Goossens J, Versées W, Caljon G, Michels PA, Walkinshaw MD, Magez S, Sterckx YG. Pinto Torres JE, et al. Among authors: michels pa. Mol Biochem Parasitol. 2020 Mar;236:111263. doi: 10.1016/j.molbiopara.2020.111263. Epub 2020 Feb 19. Mol Biochem Parasitol. 2020. PMID: 32084384

10

The first crystal structure of phosphofructokinase from a eukaryote: Trypanosoma brucei.

Martinez-Oyanedel J, McNae IW, Nowicki MW, Keillor JW, Michels PA, Fothergill-Gilmore LA, Walkinshaw MD. Martinez-Oyanedel J, et al. Among authors: michels pa. J Mol Biol. 2007 Mar 2;366(4):1185-98. doi: 10.1016/j.jmb.2006.10.019. Epub 2006 Oct 11. J Mol Biol. 2007. PMID: 17207816

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