Mao J - Search Results

1

Physiologically based pharmacokinetic modeling to predict drug-drug interactions involving inhibitory metabolite: a case study of amiodarone.

Chen Y, Mao J, Hop CE. Chen Y, et al. Among authors: mao j. Drug Metab Dispos. 2015 Feb;43(2):182-9. doi: 10.1124/dmd.114.059311. Epub 2014 Oct 16. Drug Metab Dispos. 2015. PMID: 25324279 Clinical Trial.

2

Prediction of CYP3A-mediated drug-drug interactions using human hepatocytes suspended in human plasma.

Mao J, Mohutsky MA, Harrelson JP, Wrighton SA, Hall SD. Mao J, et al. Drug Metab Dispos. 2011 Apr;39(4):591-602. doi: 10.1124/dmd.110.036400. Epub 2011 Jan 6. Drug Metab Dispos. 2011. PMID: 21212240 Free article.

3

Predictions of cytochrome P450-mediated drug-drug interactions using cryopreserved human hepatocytes: comparison of plasma and protein-free media incubation conditions.

Mao J, Mohutsky MA, Harrelson JP, Wrighton SA, Hall SD. Mao J, et al. Drug Metab Dispos. 2012 Apr;40(4):706-16. doi: 10.1124/dmd.111.043158. Epub 2012 Jan 6. Drug Metab Dispos. 2012. PMID: 22228749

4

Prediction of crizotinib-midazolam interaction using the Simcyp population-based simulator: comparison of CYP3A time-dependent inhibition between human liver microsomes versus hepatocytes.

Mao J, Johnson TR, Shen Z, Yamazaki S. Mao J, et al. Drug Metab Dispos. 2013 Feb;41(2):343-52. doi: 10.1124/dmd.112.049114. Epub 2012 Nov 5. Drug Metab Dispos. 2013. PMID: 23129213

5

Optimization of drug-drug interaction study design: comparison of minimal physiologically based pharmacokinetic models on prediction of CYP3A inhibition by ketoconazole.

Han B, Mao J, Chien JY, Hall SD. Han B, et al. Among authors: mao j. Drug Metab Dispos. 2013 Jul;41(7):1329-38. doi: 10.1124/dmd.112.050732. Epub 2013 Apr 12. Drug Metab Dispos. 2013. PMID: 23584886

6

Contribution of metabolites to P450 inhibition-based drug-drug interactions: scholarship from the drug metabolism leadership group of the innovation and quality consortium metabolite group.

Yu H, Balani SK, Chen W, Cui D, He L, Humphreys WG, Mao J, Lai WG, Lee AJ, Lim HK, MacLauchlin C, Prakash C, Surapaneni S, Tse S, Upthagrove A, Walsky RL, Wen B, Zeng Z. Yu H, et al. Among authors: mao j. Drug Metab Dispos. 2015 Apr;43(4):620-30. doi: 10.1124/dmd.114.059345. Epub 2015 Feb 5. Drug Metab Dispos. 2015. PMID: 25655830

7

In vitro and in vivo characterization of CYP inhibition by 1-aminobenzotriazole in rats.

Parrish KE, Mao J, Chen J, Jaochico A, Ly J, Ho Q, Mukadam S, Wright M. Parrish KE, et al. Among authors: mao j. Biopharm Drug Dispos. 2016 May;37(4):200-11. doi: 10.1002/bdd.2000. Biopharm Drug Dispos. 2016. PMID: 26637499

8

Development of a Physiologically Based Pharmacokinetic Model for Itraconazole Pharmacokinetics and Drug-Drug Interaction Prediction.

Chen Y, Ma F, Lu T, Budha N, Jin JY, Kenny JR, Wong H, Hop CE, Mao J. Chen Y, et al. Among authors: mao j. Clin Pharmacokinet. 2016 Jun;55(6):735-49. doi: 10.1007/s40262-015-0352-5. Clin Pharmacokinet. 2016. PMID: 26692192

9

Evaluation of Time Dependent Inhibition Assays for Marketed Oncology Drugs: Comparison of Human Hepatocytes and Liver Microsomes in the Presence and Absence of Human Plasma.

Mao J, Tay S, Khojasteh CS, Chen Y, Hop CE, Kenny JR. Mao J, et al. Pharm Res. 2016 May;33(5):1204-19. doi: 10.1007/s11095-016-1865-9. Epub 2016 Feb 11. Pharm Res. 2016. PMID: 26869174

10

Simultaneous determination of itraconazole, hydroxy itraconazole, keto itraconazole and N-desalkyl itraconazole concentration in human plasma using liquid chromatography with tandem mass spectrometry.

Liang X, Van Parys M, Ding X, Zeng N, Bi L, Dorshort D, McKnight J, Milanowski D, Mao J, Chen Y, Ware JA, Dean B, Hop CE, Deng Y. Liang X, et al. Among authors: mao j. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 May 1;1020:111-9. doi: 10.1016/j.jchromb.2016.03.039. Epub 2016 Mar 26. J Chromatogr B Analyt Technol Biomed Life Sci. 2016. PMID: 27038403

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