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Inhaled house dust mite induces pulmonary T helper 2 cytokine production.
Gregory LG, Causton B, Murdoch JR, Mathie SA, O'Donnell V, Thomas CP, Priest FM, Quint DJ, Lloyd CM. Gregory LG, et al. Clin Exp Allergy. 2009 Oct;39(10):1597-610. doi: 10.1111/j.1365-2222.2009.03302.x. Epub 2009 Jun 22. Clin Exp Allergy. 2009. PMID: 19545261 Free PMC article.
Novel keto-phospholipids are generated by monocytes and macrophages, detected in cystic fibrosis, and activate peroxisome proliferator-activated receptor-γ.
Hammond VJ, Morgan AH, Lauder S, Thomas CP, Brown S, Freeman BA, Lloyd CM, Davies J, Bush A, Levonen AL, Kansanen E, Villacorta L, Chen YE, Porter N, Garcia-Diaz YM, Schopfer FJ, O'Donnell VB. Hammond VJ, et al. J Biol Chem. 2012 Dec 7;287(50):41651-66. doi: 10.1074/jbc.M112.405407. Epub 2012 Oct 11. J Biol Chem. 2012. PMID: 23060450 Free PMC article. Clinical Trial.
Enzymatically oxidized phospholipids restore thrombin generation in coagulation factor deficiencies.
Slatter DA, Percy CL, Allen-Redpath K, Gajsiewicz JM, Brooks NJ, Clayton A, Tyrrell VJ, Rosas M, Lauder SN, Watson A, Dul M, Garcia-Diaz Y, Aldrovandi M, Heurich M, Hall J, Morrissey JH, Lacroix-Desmazes S, Delignat S, Jenkins PV, Collins PW, O'Donnell VB. Slatter DA, et al. JCI Insight. 2018 Mar 22;3(6):e98459. doi: 10.1172/jci.insight.98459. JCI Insight. 2018. PMID: 29563336 Free PMC article.
Dihomo-γ-linolenic acid inhibits several key cellular processes associated with atherosclerosis.
Gallagher H, Williams JO, Ferekidis N, Ismail A, Chan YH, Michael DR, Guschina IA, Tyrrell VJ, O'Donnell VB, Harwood JL, Khozin-Goldberg I, Boussiba S, Ramji DP. Gallagher H, et al. Biochim Biophys Acta Mol Basis Dis. 2019 Sep 1;1865(9):2538-2550. doi: 10.1016/j.bbadis.2019.06.011. Epub 2019 Jun 13. Biochim Biophys Acta Mol Basis Dis. 2019. PMID: 31202985 Free PMC article.
163 results