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Making designer mutants in model organisms.
Peng Y, Clark KJ, Campbell JM, Panetta MR, Guo Y, Ekker SC. Peng Y, et al. Among authors: guo y. Development. 2014 Nov;141(21):4042-54. doi: 10.1242/dev.102186. Development. 2014. PMID: 25336735 Free PMC article. Review.
The Rise of CRISPR/Cas for Genome Editing in Stem Cells.
Shui B, Hernandez Matias L, Guo Y, Peng Y. Shui B, et al. Among authors: guo y. Stem Cells Int. 2016;2016:8140168. doi: 10.1155/2016/8140168. Epub 2016 Jan 6. Stem Cells Int. 2016. PMID: 26880991 Free PMC article. Review.
LCK inhibition downregulates YAP activity and is therapeutic in patient-derived models of cholangiocarcinoma.
Conboy CB, Yonkus JA, Buckarma EH, Mun DG, Werneburg NW, Watkins RD, Alva-Ruiz R, Tomlinson JL, Guo Y, Wang J, O'Brien D, McCabe CE, Jessen E, Graham RP, Buijsman RC, Vu D, de Man J, Ilyas SI, Truty MJ, Borad M, Pandey A, Gores GJ, Smoot RL. Conboy CB, et al. Among authors: guo y. J Hepatol. 2023 Jan;78(1):142-152. doi: 10.1016/j.jhep.2022.09.014. Epub 2022 Sep 24. J Hepatol. 2023. PMID: 36162702 Free article.
Hepatic stellate cell activation promotes alcohol-induced steatohepatitis through Igfbp3 and SerpinA12.
Arab JP, Cabrera D, Sehrawat TS, Jalan-Sakrikar N, Verma VK, Simonetto D, Cao S, Yaqoob U, Leon J, Freire M, Vargas JI, De Assuncao TM, Kwon JH, Guo Y, Kostallari E, Cai Q, Kisseleva T, Oh Y, Arrese M, Huebert RC, Shah VH. Arab JP, et al. Among authors: guo y. J Hepatol. 2020 Jul;73(1):149-160. doi: 10.1016/j.jhep.2020.02.005. Epub 2020 Feb 20. J Hepatol. 2020. PMID: 32087348 Free PMC article.
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