Sparks LM - Search Results

1

Evidence for a direct effect of the NAD+ precursor acipimox on muscle mitochondrial function in humans.

van de Weijer T, Phielix E, Bilet L, Williams EG, Ropelle ER, Bierwagen A, Livingstone R, Nowotny P, Sparks LM, Paglialunga S, Szendroedi J, Havekes B, Moullan N, Pirinen E, Hwang JH, Schrauwen-Hinderling VB, Hesselink MK, Auwerx J, Roden M, Schrauwen P. van de Weijer T, et al. Among authors: sparks lm. Diabetes. 2015 Apr;64(4):1193-201. doi: 10.2337/db14-0667. Epub 2014 Oct 28. Diabetes. 2015. PMID: 25352640 Free PMC article. Clinical Trial.

2

A high-fat diet coordinately downregulates genes required for mitochondrial oxidative phosphorylation in skeletal muscle.

Sparks LM, Xie H, Koza RA, Mynatt R, Hulver MW, Bray GA, Smith SR. Sparks LM, et al. Diabetes. 2005 Jul;54(7):1926-33. doi: 10.2337/diabetes.54.7.1926. Diabetes. 2005. PMID: 15983191

3

Palmitate-induced skeletal muscle insulin resistance does not require NF-κB activation.

Hommelberg PP, Plat J, Sparks LM, Schols AM, van Essen AL, Kelders MC, van Beurden D, Mensink RP, Langen RC. Hommelberg PP, et al. Among authors: sparks lm. Cell Mol Life Sci. 2011 Apr;68(7):1215-25. doi: 10.1007/s00018-010-0515-3. Epub 2010 Sep 5. Cell Mol Life Sci. 2011. PMID: 20820848 Free PMC article.

4

Transcriptional metabolic inflexibility in skeletal muscle among individuals with increasing insulin resistance.

Jans A, Sparks LM, van Hees AM, Gjelstad IM, Tierney AC, Risérus U, Drevon CA, Roche HM, Schrauwen P, Blaak EE. Jans A, et al. Among authors: sparks lm. Obesity (Silver Spring). 2011 Nov;19(11):2158-66. doi: 10.1038/oby.2011.149. Epub 2011 Jun 23. Obesity (Silver Spring). 2011. PMID: 21701566 Free article.

5

The lipid droplet coat protein perilipin 5 also localizes to muscle mitochondria.

Bosma M, Minnaard R, Sparks LM, Schaart G, Losen M, de Baets MH, Duimel H, Kersten S, Bickel PE, Schrauwen P, Hesselink MK. Bosma M, et al. Among authors: sparks lm. Histochem Cell Biol. 2012 Feb;137(2):205-16. doi: 10.1007/s00418-011-0888-x. Epub 2011 Nov 30. Histochem Cell Biol. 2012. PMID: 22127648 Free PMC article.

6

Impact of dietary fat quantity and quality on skeletal muscle fatty acid metabolism in subjects with the metabolic syndrome.

Jans A, van Hees AM, Gjelstad IM, Sparks LM, Tierney AC, Risérus U, Drevon CA, Schrauwen P, Roche HM, Blaak EE. Jans A, et al. Among authors: sparks lm. Metabolism. 2012 Nov;61(11):1554-65. doi: 10.1016/j.metabol.2012.04.003. Epub 2012 Jun 1. Metabolism. 2012. PMID: 22658938 Clinical Trial.

7

High oxidative capacity due to chronic exercise training attenuates lipid-induced insulin resistance.

Phielix E, Meex R, Ouwens DM, Sparks L, Hoeks J, Schaart G, Moonen-Kornips E, Hesselink MK, Schrauwen P. Phielix E, et al. Diabetes. 2012 Oct;61(10):2472-8. doi: 10.2337/db11-1832. Epub 2012 Jul 10. Diabetes. 2012. PMID: 22787138 Free PMC article.

8

Perilipin 2 improves insulin sensitivity in skeletal muscle despite elevated intramuscular lipid levels.

Bosma M, Hesselink MK, Sparks LM, Timmers S, Ferraz MJ, Mattijssen F, van Beurden D, Schaart G, de Baets MH, Verheyen FK, Kersten S, Schrauwen P. Bosma M, et al. Among authors: sparks lm. Diabetes. 2012 Nov;61(11):2679-90. doi: 10.2337/db11-1402. Epub 2012 Jul 17. Diabetes. 2012. PMID: 22807032 Free PMC article.

9

PPARγ coactivator-1α contributes to exercise-induced regulation of intramuscular lipid droplet programming in mice and humans.

Koves TR, Sparks LM, Kovalik JP, Mosedale M, Arumugam R, DeBalsi KL, Everingham K, Thorne L, Phielix E, Meex RC, Kien CL, Hesselink MK, Schrauwen P, Muoio DM. Koves TR, et al. Among authors: sparks lm. J Lipid Res. 2013 Feb;54(2):522-34. doi: 10.1194/jlr.P028910. Epub 2012 Nov 21. J Lipid Res. 2013. PMID: 23175776 Free PMC article.

10

Overexpression of PLIN5 in skeletal muscle promotes oxidative gene expression and intramyocellular lipid content without compromising insulin sensitivity.

Bosma M, Sparks LM, Hooiveld GJ, Jorgensen JA, Houten SM, Schrauwen P, Kersten S, Hesselink MK. Bosma M, et al. Among authors: sparks lm. Biochim Biophys Acta. 2013 Apr;1831(4):844-52. doi: 10.1016/j.bbalip.2013.01.007. Epub 2013 Jan 22. Biochim Biophys Acta. 2013. PMID: 23353597

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