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Circular trimers of gelatinase B/matrix metalloproteinase-9 constitute a distinct population of functional enzyme molecules differentially regulated by tissue inhibitor of metalloproteinases-1.
Vandooren J, Born B, Solomonov I, Zajac E, Saldova R, Senske M, Ugarte-Berzal E, Martens E, Van den Steen PE, Van Damme J, Garcia-Pardo A, Froeyen M, Deryugina EI, Quigley JP, Moestrup SK, Rudd PM, Sagi I, Opdenakker G. Vandooren J, et al. Among authors: froeyen m. Biochem J. 2015 Jan 15;465(2):259-70. doi: 10.1042/BJ20140418. Biochem J. 2015. PMID: 25360794 Free PMC article.
A pyrazolotriazolopyrimidinamine inhibitor of bovine viral diarrhea virus replication that targets the viral RNA-dependent RNA polymerase.
Paeshuyse J, Letellier C, Froeyen M, Dutartre H, Vrancken R, Canard B, De Clercq E, Gueiffier A, Teulade JC, Herdewijn P, Puerstinger G, Koenen F, Kerkhofs P, Baraldi PG, Neyts J. Paeshuyse J, et al. Among authors: froeyen m. Antiviral Res. 2009 Jun;82(3):141-7. doi: 10.1016/j.antiviral.2009.02.192. Epub 2009 Feb 27. Antiviral Res. 2009. PMID: 19428605
A novel, highly selective inhibitor of pestivirus replication that targets the viral RNA-dependent RNA polymerase.
Paeshuyse J, Leyssen P, Mabery E, Boddeker N, Vrancken R, Froeyen M, Ansari IH, Dutartre H, Rozenski J, Gil LH, Letellier C, Lanford R, Canard B, Koenen F, Kerkhofs P, Donis RO, Herdewijn P, Watson J, De Clercq E, Puerstinger G, Neyts J. Paeshuyse J, et al. Among authors: froeyen m. J Virol. 2006 Jan;80(1):149-60. doi: 10.1128/JVI.80.1.149-160.2006. J Virol. 2006. PMID: 16352539 Free PMC article.
The imidazopyrrolopyridine analogue AG110 is a novel, highly selective inhibitor of pestiviruses that targets the viral RNA-dependent RNA polymerase at a hot spot for inhibition of viral replication.
Paeshuyse J, Chezal JM, Froeyen M, Leyssen P, Dutartre H, Vrancken R, Canard B, Letellier C, Li T, Mittendorfer H, Koenen F, Kerkhofs P, De Clercq E, Herdewijn P, Puerstinger G, Gueiffier A, Chavignon O, Teulade JC, Neyts J. Paeshuyse J, et al. Among authors: froeyen m. J Virol. 2007 Oct;81(20):11046-53. doi: 10.1128/JVI.00388-07. Epub 2007 Aug 8. J Virol. 2007. PMID: 17686854 Free PMC article.
129 results