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15,575 results

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Preclinical efficacy of MEK inhibition in Nras-mutant AML.
Burgess MR, Hwang E, Firestone AJ, Huang T, Xu J, Zuber J, Bohin N, Wen T, Kogan SC, Haigis KM, Sampath D, Lowe S, Shannon K, Li Q. Burgess MR, et al. Among authors: huang t. Blood. 2014 Dec 18;124(26):3947-55. doi: 10.1182/blood-2014-05-574582. Epub 2014 Oct 31. Blood. 2014. PMID: 25361812 Free PMC article.
KrasP34R and KrasT58I mutations induce distinct RASopathy phenotypes in mice.
Wong JC, Perez-Mancera PA, Huang TQ, Kim J, Grego-Bessa J, Del Pilar Alzamora M, Kogan SC, Sharir A, Keefe SH, Morales CE, Schanze D, Castel P, Hirose K, Huang GN, Zenker M, Sheppard D, Klein OD, Tuveson DA, Braun BS, Shannon K. Wong JC, et al. JCI Insight. 2020 Nov 5;5(21):e140495. doi: 10.1172/jci.insight.140495. JCI Insight. 2020. PMID: 32990679 Free PMC article.
Targeting the PI3K/Akt pathway in murine MDS/MPN driven by hyperactive Ras.
Akutagawa J, Huang TQ, Epstein I, Chang T, Quirindongo-Crespo M, Cottonham CL, Dail M, Slusher BS, Friedman LS, Sampath D, Braun BS. Akutagawa J, et al. Among authors: huang tq. Leukemia. 2016 Jun;30(6):1335-43. doi: 10.1038/leu.2016.14. Epub 2016 Feb 12. Leukemia. 2016. PMID: 26965285 Free PMC article.
Tissue-Specific Oncogenic Activity of KRASA146T.
Poulin EJ, Bera AK, Lu J, Lin YJ, Strasser SD, Paulo JA, Huang TQ, Morales C, Yan W, Cook J, Nowak JA, Brubaker DK, Joughin BA, Johnson CW, DeStefanis RA, Ghazi PC, Gondi S, Wales TE, Iacob RE, Bogdanova L, Gierut JJ, Li Y, Engen JR, Perez-Mancera PA, Braun BS, Gygi SP, Lauffenburger DA, Westover KD, Haigis KM. Poulin EJ, et al. Cancer Discov. 2019 Jun;9(6):738-755. doi: 10.1158/2159-8290.CD-18-1220. Epub 2019 Apr 5. Cancer Discov. 2019. PMID: 30952657 Free PMC article.
A Collaborative Model for Accelerating the Discovery and Translation of Cancer Therapies.
Maertens O, McCurrach ME, Braun BS, De Raedt T, Epstein I, Huang TQ, Lauchle JO, Lee H, Wu J, Cripe TP, Clapp DW, Ratner N, Shannon K, Cichowski K. Maertens O, et al. Among authors: huang tq. Cancer Res. 2017 Nov 1;77(21):5706-5711. doi: 10.1158/0008-5472.CAN-17-1789. Epub 2017 Oct 9. Cancer Res. 2017. PMID: 28993414 Free PMC article. Review.
Multidisciplinary care of patients with brain tumors.
Huang T, Mueller S, Rutkowski MJ, Han SJ, Bloch O, Barani IJ, Parsa AT, Chang SM. Huang T, et al. Surg Oncol Clin N Am. 2013 Apr;22(2):161-78. doi: 10.1016/j.soc.2012.12.011. Epub 2013 Jan 10. Surg Oncol Clin N Am. 2013. PMID: 23453330 Review.
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