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Antitumor activity of the MEK inhibitor TAK-733 against melanoma cell lines and patient-derived tumor explants.
Mol Cancer Ther. 2015 Feb;14(2):317-25. doi: 10.1158/1535-7163.MCT-13-1012. Epub 2014 Nov 5.
Mol Cancer Ther. 2015.
PMID: 25376610
Free PMC article.
Rational combination of a MEK inhibitor, selumetinib, and the Wnt/calcium pathway modulator, cyclosporin A, in preclinical models of colorectal cancer.
Spreafico A, Tentler JJ, Pitts TM, Tan AC, Gregory MA, Arcaroli JJ, Klauck PJ, McManus MC, Hansen RJ, Kim J, Micel LN, Selby HM, Newton TP, McPhillips KL, Gustafson DL, Degregori JV, Messersmith WA, Winn RA, Eckhardt SG.
Spreafico A, et al. Among authors: micel ln.
Clin Cancer Res. 2013 Aug 1;19(15):4149-62. doi: 10.1158/1078-0432.CCR-12-3140. Epub 2013 Jun 11.
Clin Cancer Res. 2013.
PMID: 23757356
Free PMC article.
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Targeting the protein ubiquitination machinery in melanoma by the NEDD8-activating enzyme inhibitor pevonedistat (MLN4924).
Wong KM, Micel LN, Selby HM, Tan AC, Pitts TM, Bagby SM, Spreafico A, Klauck PJ, Blakemore SJ, Smith PF, McDonald A, Berger A, Tentler JJ, Eckhardt SG.
Wong KM, et al. Among authors: micel ln.
Invest New Drugs. 2017 Feb;35(1):11-25. doi: 10.1007/s10637-016-0398-8. Epub 2016 Oct 25.
Invest New Drugs. 2017.
PMID: 27783255
Free PMC article.
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Role of ubiquitin ligases and the proteasome in oncogenesis: novel targets for anticancer therapies.
Micel LN, Tentler JJ, Smith PG, Eckhardt GS.
Micel LN, et al.
J Clin Oncol. 2013 Mar 20;31(9):1231-8. doi: 10.1200/JCO.2012.44.0958. Epub 2013 Jan 28.
J Clin Oncol. 2013.
PMID: 23358974
Free PMC article.
Review.
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Ethanol locks therapy for resolution of fungal catheter infections.
Blackwood RA, Klein KC, Micel LN, Willers ML, Mody RJ, Teitelbaum DH, Cober MP.
Blackwood RA, et al. Among authors: micel ln.
Pediatr Infect Dis J. 2011 Dec;30(12):1105-7. doi: 10.1097/INF.0b013e31822c84a4.
Pediatr Infect Dis J. 2011.
PMID: 21844829
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