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Coexistent hyperdiploidy does not abrogate poor prognosis in myeloma with adverse cytogenetics and may precede IGH translocations.
Pawlyn C, Melchor L, Murison A, Wardell CP, Brioli A, Boyle EM, Kaiser MF, Walker BA, Begum DB, Dahir NB, Proszek P, Gregory WM, Drayson MT, Jackson GH, Ross FM, Davies FE, Morgan GJ. Pawlyn C, et al. Among authors: wardell cp. Blood. 2015 Jan 29;125(5):831-40. doi: 10.1182/blood-2014-07-584268. Epub 2014 Nov 26. Blood. 2015. PMID: 25428216 Free PMC article. Clinical Trial.
Neutral tumor evolution in myeloma is associated with poor prognosis.
Johnson DC, Lenive O, Mitchell J, Jackson G, Owen R, Drayson M, Cook G, Jones JR, Pawlyn C, Davies FE, Walker BA, Wardell C, Gregory WM, Cairns D, Morgan GJ, Houlston RS, Kaiser MF. Johnson DC, et al. Blood. 2017 Oct 5;130(14):1639-1643. doi: 10.1182/blood-2016-11-750612. Epub 2017 Aug 21. Blood. 2017. PMID: 28827410 Free PMC article. Clinical Trial.
Gender disparities in the tumor genetics and clinical outcome of multiple myeloma.
Boyd KD, Ross FM, Chiecchio L, Dagrada G, Konn ZJ, Tapper WJ, Walker BA, Wardell CP, Gregory WM, Szubert AJ, Davies FE, Morgan GJ. Boyd KD, et al. Among authors: wardell cp. Cancer Epidemiol Biomarkers Prev. 2011 Aug;20(8):1703-7. doi: 10.1158/1055-9965.EPI-11-0157. Epub 2011 Jun 15. Cancer Epidemiol Biomarkers Prev. 2011. PMID: 21680536 Free PMC article. Clinical Trial.
Mapping of chromosome 1p deletions in myeloma identifies FAM46C at 1p12 and CDKN2C at 1p32.3 as being genes in regions associated with adverse survival.
Boyd KD, Ross FM, Walker BA, Wardell CP, Tapper WJ, Chiecchio L, Dagrada G, Konn ZJ, Gregory WM, Jackson GH, Child JA, Davies FE, Morgan GJ; NCRI Haematology Oncology Studies Group. Boyd KD, et al. Among authors: wardell cp. Clin Cancer Res. 2011 Dec 15;17(24):7776-84. doi: 10.1158/1078-0432.CCR-11-1791. Epub 2011 Oct 12. Clin Cancer Res. 2011. PMID: 21994415 Free PMC article.
65 results