Redwood CS - Search Results

1

Changes in the cardiac metabolome caused by perhexiline treatment in a mouse model of hypertrophic cardiomyopathy.

Gehmlich K, Dodd MS, Allwood JW, Kelly M, Bellahcene M, Lad HV, Stockenhuber A, Hooper C, Ashrafian H, Redwood CS, Carrier L, Dunn WB. Gehmlich K, et al. Among authors: redwood cs. Mol Biosyst. 2015 Feb;11(2):564-73. doi: 10.1039/c4mb00594e. Mol Biosyst. 2015. PMID: 25437646

2

Properties of mutant contractile proteins that cause hypertrophic cardiomyopathy.

Redwood CS, Moolman-Smook JC, Watkins H. Redwood CS, et al. Cardiovasc Res. 1999 Oct;44(1):20-36. doi: 10.1016/s0008-6363(99)00213-8. Cardiovasc Res. 1999. PMID: 10615387 Review.

3

Altered regulatory properties of human cardiac troponin I mutants that cause hypertrophic cardiomyopathy.

Elliott K, Watkins H, Redwood CS. Elliott K, et al. Among authors: redwood cs. J Biol Chem. 2000 Jul 21;275(29):22069-74. doi: 10.1074/jbc.M002502200. J Biol Chem. 2000. PMID: 10806205 Free article.

4

Mutations in the gamma(2) subunit of AMP-activated protein kinase cause familial hypertrophic cardiomyopathy: evidence for the central role of energy compromise in disease pathogenesis.

Blair E, Redwood C, Ashrafian H, Oliveira M, Broxholme J, Kerr B, Salmon A, Ostman-Smith I, Watkins H. Blair E, et al. Hum Mol Genet. 2001 May 15;10(11):1215-20. doi: 10.1093/hmg/10.11.1215. Hum Mol Genet. 2001. PMID: 11371514

5

Hypertrophic cardiomyopathy:a paradigm for myocardial energy depletion.

Ashrafian H, Redwood C, Blair E, Watkins H. Ashrafian H, et al. Trends Genet. 2003 May;19(5):263-8. doi: 10.1016/S0168-9525(03)00081-7. Trends Genet. 2003. PMID: 12711218 Review.

6

Dilated and hypertrophic cardiomyopathy mutations in troponin and alpha-tropomyosin have opposing effects on the calcium affinity of cardiac thin filaments.

Robinson P, Griffiths PJ, Watkins H, Redwood CS. Robinson P, et al. Among authors: redwood cs. Circ Res. 2007 Dec 7;101(12):1266-73. doi: 10.1161/CIRCRESAHA.107.156380. Epub 2007 Oct 11. Circ Res. 2007. PMID: 17932326

7

Investigation of a transgenic mouse model of familial dilated cardiomyopathy.

Song W, Dyer E, Stuckey D, Leung MC, Memo M, Mansfield C, Ferenczi M, Liu K, Redwood C, Nowak K, Harding S, Clarke K, Wells D, Marston S. Song W, et al. J Mol Cell Cardiol. 2010 Sep;49(3):380-9. doi: 10.1016/j.yjmcc.2010.05.009. Epub 2010 Jun 17. J Mol Cell Cardiol. 2010. PMID: 20600154

8

Normal passive viscoelasticity but abnormal myofibrillar force generation in human hypertrophic cardiomyopathy.

Hoskins AC, Jacques A, Bardswell SC, McKenna WJ, Tsang V, dos Remedios CG, Ehler E, Adams K, Jalilzadeh S, Avkiran M, Watkins H, Redwood C, Marston SB, Kentish JC. Hoskins AC, et al. J Mol Cell Cardiol. 2010 Nov;49(5):737-45. doi: 10.1016/j.yjmcc.2010.06.006. Epub 2010 Jul 6. J Mol Cell Cardiol. 2010. PMID: 20615414 Free PMC article.

9

Inherited cardiomyopathies.

Watkins H, Ashrafian H, Redwood C. Watkins H, et al. N Engl J Med. 2011 Apr 28;364(17):1643-56. doi: 10.1056/NEJMra0902923. N Engl J Med. 2011. PMID: 21524215 Free article. Review. No abstract available.

10

Fumarate is cardioprotective via activation of the Nrf2 antioxidant pathway.

Ashrafian H, Czibik G, Bellahcene M, Aksentijević D, Smith AC, Mitchell SJ, Dodd MS, Kirwan J, Byrne JJ, Ludwig C, Isackson H, Yavari A, Støttrup NB, Contractor H, Cahill TJ, Sahgal N, Ball DR, Birkler RI, Hargreaves I, Tennant DA, Land J, Lygate CA, Johannsen M, Kharbanda RK, Neubauer S, Redwood C, de Cabo R, Ahmet I, Talan M, Günther UL, Robinson AJ, Viant MR, Pollard PJ, Tyler DJ, Watkins H. Ashrafian H, et al. Cell Metab. 2012 Mar 7;15(3):361-71. doi: 10.1016/j.cmet.2012.01.017. Cell Metab. 2012. PMID: 22405071 Free PMC article.

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