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Isolation and characterization of a protease inhibitor from Acacia karroo with a common combining loop and overlapping binding sites for chymotrypsin and trypsin.
Arch Biochem Biophys. 2015 Jan 1;565:9-16. doi: 10.1016/j.abb.2014.11.001. Epub 2014 Nov 8.
Arch Biochem Biophys. 2015.
PMID: 25447841
The catalytic aspartate is protonated in the Michaelis complex formed between trypsin and an in vitro evolved substrate-like inhibitor: a refined mechanism of serine protease action.
Wahlgren WY, Pál G, Kardos J, Porrogi P, Szenthe B, Patthy A, Gráf L, Katona G.
Wahlgren WY, et al. Among authors: porrogi p.
J Biol Chem. 2011 Feb 4;286(5):3587-96. doi: 10.1074/jbc.M110.161604. Epub 2010 Nov 21.
J Biol Chem. 2011.
PMID: 21097875
Free PMC article.
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Limited applicability of 7-methoxy-4-trifluoromethylcoumarin as a CYP2C9-selective substrate.
Porrogi P, Kóbori L, Kõhalmy K, Gulyás J, Vereczkey L, Monostory K.
Porrogi P, et al.
Pharmacol Rep. 2008 Nov-Dec;60(6):972-9.
Pharmacol Rep. 2008.
PMID: 19211991
Free article.
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Dehydroepiandrosterone induces human CYP2B6 through the constitutive androstane receptor.
Kohalmy K, Tamási V, Kóbori L, Sárváry E, Pascussi JM, Porrogi P, Rozman D, Prough RA, Meyer UA, Monostory K.
Kohalmy K, et al. Among authors: porrogi p.
Drug Metab Dispos. 2007 Sep;35(9):1495-501. doi: 10.1124/dmd.107.016303. Epub 2007 Jun 25.
Drug Metab Dispos. 2007.
PMID: 17591676
Free PMC article.
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Drug-induced liver graft toxicity caused by cytochrome P450 poor metabolism.
Kóbori L, Kõhalmy K, Porrogi P, Sárváry E, Gerlei Z, Fazakas J, Nagy P, Járay J, Monostory K.
Kóbori L, et al. Among authors: porrogi p.
Br J Clin Pharmacol. 2008 Mar;65(3):428-36. doi: 10.1111/j.1365-2125.2007.03056.x. Epub 2007 Dec 7.
Br J Clin Pharmacol. 2008.
PMID: 18070218
Free PMC article.
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Dehydroepiandrosterone post-transcriptionally modifies CYP1A2 induction involving androgen receptor.
Belic A, Tóth K, Vrzal R, Temesvári M, Porrogi P, Orbán E, Rozman D, Dvorak Z, Monostory K.
Belic A, et al. Among authors: porrogi p.
Chem Biol Interact. 2013 May 25;203(3):597-603. doi: 10.1016/j.cbi.2013.04.002. Epub 2013 Apr 17.
Chem Biol Interact. 2013.
PMID: 23603339
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