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Mitochondria in peroxisome-deficient hepatocytes exhibit impaired respiration, depleted DNA, and PGC-1α independent proliferation.
Peeters A, Shinde AB, Dirkx R, Smet J, De Bock K, Espeel M, Vanhorebeek I, Vanlander A, Van Coster R, Carmeliet P, Fransen M, Van Veldhoven PP, Baes M. Peeters A, et al. Among authors: carmeliet p. Biochim Biophys Acta. 2015 Feb;1853(2):285-98. doi: 10.1016/j.bbamcr.2014.11.017. Epub 2014 Nov 20. Biochim Biophys Acta. 2015. PMID: 25450972 Free article.
A mouse model for Zellweger syndrome.
Baes M, Gressens P, Baumgart E, Carmeliet P, Casteels M, Fransen M, Evrard P, Fahimi D, Declercq PE, Collen D, van Veldhoven PP, Mannaerts GP. Baes M, et al. Among authors: carmeliet p. Nat Genet. 1997 Sep;17(1):49-57. doi: 10.1038/ng0997-49. Nat Genet. 1997. PMID: 9288097
Neuronal migration depends on intact peroxisomal function in brain and in extraneuronal tissues.
Janssen A, Gressens P, Grabenbauer M, Baumgart E, Schad A, Vanhorebeek I, Brouwers A, Declercq PE, Fahimi D, Evrard P, Schoonjans L, Collen D, Carmeliet P, Mannaerts G, Van Veldhoven P, Baes M. Janssen A, et al. Among authors: carmeliet p. J Neurosci. 2003 Oct 29;23(30):9732-41. doi: 10.1523/JNEUROSCI.23-30-09732.2003. J Neurosci. 2003. PMID: 14586000 Free PMC article.
Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism.
Aragonés J, Schneider M, Van Geyte K, Fraisl P, Dresselaers T, Mazzone M, Dirkx R, Zacchigna S, Lemieux H, Jeoung NH, Lambrechts D, Bishop T, Lafuste P, Diez-Juan A, Harten SK, Van Noten P, De Bock K, Willam C, Tjwa M, Grosfeld A, Navet R, Moons L, Vandendriessche T, Deroose C, Wijeyekoon B, Nuyts J, Jordan B, Silasi-Mansat R, Lupu F, Dewerchin M, Pugh C, Salmon P, Mortelmans L, Gallez B, Gorus F, Buyse J, Sluse F, Harris RA, Gnaiger E, Hespel P, Van Hecke P, Schuit F, Van Veldhoven P, Ratcliffe P, Baes M, Maxwell P, Carmeliet P. Aragonés J, et al. Among authors: carmeliet p. Nat Genet. 2008 Feb;40(2):170-80. doi: 10.1038/ng.2007.62. Epub 2008 Jan 6. Nat Genet. 2008. PMID: 18176562 Free article.
Metabolism and therapeutic angiogenesis.
Carmeliet P, Baes M. Carmeliet P, et al. N Engl J Med. 2008 Jun 5;358(23):2511-2. doi: 10.1056/NEJMcibr0802500. N Engl J Med. 2008. PMID: 18525050 No abstract available.
Oxygen sensors at the crossroad of metabolism.
Aragonés J, Fraisl P, Baes M, Carmeliet P. Aragonés J, et al. Among authors: carmeliet p. Cell Metab. 2009 Jan 7;9(1):11-22. doi: 10.1016/j.cmet.2008.10.001. Cell Metab. 2009. PMID: 19117543 Free article. Review.
783 results