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Heme oxygenase-1 acts as an antiviral factor for porcine reproductive and respiratory syndrome virus infection and over-expression inhibits virus replication in vitro.
Xiao S, Zhang A, Zhang C, Ni H, Gao J, Wang C, Zhao Q, Wang X, Wang X, Ma C, Liu H, Li N, Mu Y, Sun Y, Zhang G, Hiscox JA, Hsu WH, Zhou EM. Xiao S, et al. Among authors: hiscox ja. Antiviral Res. 2014 Oct;110:60-9. doi: 10.1016/j.antiviral.2014.07.011. Epub 2014 Jul 30. Antiviral Res. 2014. PMID: 25086213
Resolution of the cellular proteome of the nucleocapsid protein from a highly pathogenic isolate of porcine reproductive and respiratory syndrome virus identifies PARP-1 as a cellular target whose interaction is critical for virus biology.
Liu L, Lear Z, Hughes DJ, Wu W, Zhou EM, Whitehouse A, Chen H, Hiscox JA. Liu L, et al. Among authors: hiscox ja. Vet Microbiol. 2015 Mar 23;176(1-2):109-19. doi: 10.1016/j.vetmic.2014.11.023. Epub 2014 Dec 30. Vet Microbiol. 2015. PMID: 25614100 Free PMC article.
MicroRNA miR-24-3p promotes porcine reproductive and respiratory syndrome virus replication through suppression of heme oxygenase-1 expression.
Xiao S, Wang X, Ni H, Li N, Zhang A, Liu H, Pu F, Xu L, Gao J, Zhao Q, Mu Y, Wang C, Sun Y, Du T, Xu X, Zhang G, Hiscox JA, Goodfellow IG, Zhou EM. Xiao S, et al. Among authors: hiscox ja. J Virol. 2015 Apr;89(8):4494-503. doi: 10.1128/JVI.02810-14. Epub 2015 Feb 4. J Virol. 2015. PMID: 25653454 Free PMC article.
Glycoprotein 5 of porcine reproductive and respiratory syndrome virus strain SD16 inhibits viral replication and causes G2/M cell cycle arrest, but does not induce cellular apoptosis in Marc-145 cells.
Mu Y, Li L, Zhang B, Huang B, Gao J, Wang X, Wang C, Xiao S, Zhao Q, Sun Y, Zhang G, Hiscox JA, Zhou EM. Mu Y, et al. Among authors: hiscox ja. Virology. 2015 Oct;484:136-145. doi: 10.1016/j.virol.2015.05.019. Epub 2015 Jun 19. Virology. 2015. PMID: 26093497 Free article.
Characterization of the Interactome of the Porcine Reproductive and Respiratory Syndrome Virus Nonstructural Protein 2 Reveals the Hyper Variable Region as a Binding Platform for Association with 14-3-3 Proteins.
Xiao Y, Wu W, Gao J, Smith N, Burkard C, Xia D, Zhang M, Wang C, Archibald A, Digard P, Zhou EM, Hiscox JA. Xiao Y, et al. Among authors: hiscox ja. J Proteome Res. 2016 May 6;15(5):1388-401. doi: 10.1021/acs.jproteome.5b00396. Epub 2016 Apr 12. J Proteome Res. 2016. PMID: 26709850
202 results