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Role of PFKFB3-driven glycolysis in vessel sprouting.
De Bock K, Georgiadou M, Schoors S, Kuchnio A, Wong BW, Cantelmo AR, Quaegebeur A, Ghesquière B, Cauwenberghs S, Eelen G, Phng LK, Betz I, Tembuyser B, Brepoels K, Welti J, Geudens I, Segura I, Cruys B, Bifari F, Decimo I, Blanco R, Wyns S, Vangindertael J, Rocha S, Collins RT, Munck S, Daelemans D, Imamura H, Devlieger R, Rider M, Van Veldhoven PP, Schuit F, Bartrons R, Hofkens J, Fraisl P, Telang S, Deberardinis RJ, Schoonjans L, Vinckier S, Chesney J, Gerhardt H, Dewerchin M, Carmeliet P. De Bock K, et al. Among authors: carmeliet p. Cell. 2013 Aug 1;154(3):651-63. doi: 10.1016/j.cell.2013.06.037. Cell. 2013. PMID: 23911327 Free article.
The fragile X protein binds mRNAs involved in cancer progression and modulates metastasis formation.
Lucá R, Averna M, Zalfa F, Vecchi M, Bianchi F, La Fata G, Del Nonno F, Nardacci R, Bianchi M, Nuciforo P, Munck S, Parrella P, Moura R, Signori E, Alston R, Kuchnio A, Farace MG, Fazio VM, Piacentini M, De Strooper B, Achsel T, Neri G, Neven P, Evans DG, Carmeliet P, Mazzone M, Bagni C. Lucá R, et al. Among authors: carmeliet p. EMBO Mol Med. 2013 Oct;5(10):1523-36. doi: 10.1002/emmm.201302847. Epub 2013 Sep 16. EMBO Mol Med. 2013. PMID: 24092663 Free PMC article.
Partial and transient reduction of glycolysis by PFKFB3 blockade reduces pathological angiogenesis.
Schoors S, De Bock K, Cantelmo AR, Georgiadou M, Ghesquière B, Cauwenberghs S, Kuchnio A, Wong BW, Quaegebeur A, Goveia J, Bifari F, Wang X, Blanco R, Tembuyser B, Cornelissen I, Bouché A, Vinckier S, Diaz-Moralli S, Gerhardt H, Telang S, Cascante M, Chesney J, Dewerchin M, Carmeliet P. Schoors S, et al. Among authors: carmeliet p. Cell Metab. 2014 Jan 7;19(1):37-48. doi: 10.1016/j.cmet.2013.11.008. Epub 2013 Dec 12. Cell Metab. 2014. PMID: 24332967 Free article.
Hypoxia induces VEGF-C expression in metastatic tumor cells via a HIF-1α-independent translation-mediated mechanism.
Morfoisse F, Kuchnio A, Frainay C, Gomez-Brouchet A, Delisle MB, Marzi S, Helfer AC, Hantelys F, Pujol F, Guillermet-Guibert J, Bousquet C, Dewerchin M, Pyronnet S, Prats AC, Carmeliet P, Garmy-Susini B. Morfoisse F, et al. Among authors: carmeliet p. Cell Rep. 2014 Jan 16;6(1):155-67. doi: 10.1016/j.celrep.2013.12.011. Epub 2014 Jan 2. Cell Rep. 2014. PMID: 24388748 Free article.
Metabolism of stromal and immune cells in health and disease.
Ghesquière B, Wong BW, Kuchnio A, Carmeliet P. Ghesquière B, et al. Among authors: carmeliet p. Nature. 2014 Jul 10;511(7508):167-76. doi: 10.1038/nature13312. Nature. 2014. PMID: 25008522 Free article. Review.
Tumor vessel normalization by chloroquine independent of autophagy.
Maes H, Kuchnio A, Peric A, Moens S, Nys K, De Bock K, Quaegebeur A, Schoors S, Georgiadou M, Wouters J, Vinckier S, Vankelecom H, Garmyn M, Vion AC, Radtke F, Boulanger C, Gerhardt H, Dejana E, Dewerchin M, Ghesquière B, Annaert W, Agostinis P, Carmeliet P. Maes H, et al. Among authors: carmeliet p. Cancer Cell. 2014 Aug 11;26(2):190-206. doi: 10.1016/j.ccr.2014.06.025. Cancer Cell. 2014. PMID: 25117709 Free article.
773 results