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Signaling via G proteins mediates tumorigenic effects of GPR87.
Niss Arfelt K, Fares S, Sparre-Ulrich AH, Hjortø GM, Gasbjerg LS, Mølleskov-Jensen AS, Benned-Jensen T, Rosenkilde MM. Niss Arfelt K, et al. Cell Signal. 2017 Jan;30:9-18. doi: 10.1016/j.cellsig.2016.11.009. Epub 2016 Nov 16. Cell Signal. 2017. PMID: 27865873
Human GIP(3-30)NH2 inhibits G protein-dependent as well as G protein-independent signaling and is selective for the GIP receptor with high-affinity binding to primate but not rodent GIP receptors.
Gabe MBN, Sparre-Ulrich AH, Pedersen MF, Gasbjerg LS, Inoue A, Bräuner-Osborne H, Hartmann B, Rosenkilde MM. Gabe MBN, et al. Among authors: sparre ulrich ah. Biochem Pharmacol. 2018 Apr;150:97-107. doi: 10.1016/j.bcp.2018.01.040. Epub 2018 Feb 3. Biochem Pharmacol. 2018. PMID: 29378179
Investigating GIPR (ant)agonism: A structural analysis of GIP and its receptor.
Smit FX, van der Velden WJC, Kizilkaya HS, Nørskov A, Lückmann M, Hansen TN, Sparre-Ulrich AH, Qvotrup K, Frimurer TM, Rosenkilde MM. Smit FX, et al. Among authors: sparre ulrich ah. Structure. 2021 Jul 1;29(7):679-693.e6. doi: 10.1016/j.str.2021.04.001. Epub 2021 Apr 22. Structure. 2021. PMID: 33891864 Free article.
24 results