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IL-18 Immunotherapy for Neovascular AMD: Tolerability and Efficacy in Nonhuman Primates.
Doyle SL, López FJ, Celkova L, Brennan K, Mulfaul K, Ozaki E, Kenna PF, Kurali E, Hudson N, Doggett T, Ferguson TA, Humphries P, Adamson P, Campbell M. Doyle SL, et al. Among authors: adamson p. Invest Ophthalmol Vis Sci. 2015 Aug;56(9):5424-30. doi: 10.1167/iovs.15-17264. Invest Ophthalmol Vis Sci. 2015. PMID: 26284546
Author Response: The Role of IL-18 in the Treatment of AMD.
Doyle SL, López FJ, Humphries P, Adamson P, Campbell M. Doyle SL, et al. Among authors: adamson p. Invest Ophthalmol Vis Sci. 2015 Dec;56(13):8237-8. doi: 10.1167/iovs.15-18714. Invest Ophthalmol Vis Sci. 2015. PMID: 26720477 No abstract available.
IL-18 attenuates experimental choroidal neovascularization as a potential therapy for wet age-related macular degeneration.
Doyle SL, Ozaki E, Brennan K, Humphries MM, Mulfaul K, Keaney J, Kenna PF, Maminishkis A, Kiang AS, Saunders SP, Hams E, Lavelle EC, Gardiner C, Fallon PG, Adamson P, Humphries P, Campbell M. Doyle SL, et al. Among authors: adamson p. Sci Transl Med. 2014 Apr 2;6(230):230ra44. doi: 10.1126/scitranslmed.3007616. Sci Transl Med. 2014. PMID: 24695684
Systemic administration of Abeta mAb reduces retinal deposition of Abeta and activated complement C3 in age-related macular degeneration mouse model.
Catchpole I, Germaschewski V, Hoh Kam J, Lundh von Leithner P, Ford S, Gough G, Adamson P, Overend P, Hilpert J, López FJ, Ng YS, Coffey P, Jeffery G. Catchpole I, et al. Among authors: adamson p. PLoS One. 2013 Jun 14;8(6):e65518. doi: 10.1371/journal.pone.0065518. Print 2013. PLoS One. 2013. PMID: 23799019 Free PMC article.
Lipoprotein-associated phospholipase A2 (Lp-PLA2) as a therapeutic target to prevent retinal vasopermeability during diabetes.
Canning P, Kenny BA, Prise V, Glenn J, Sarker MH, Hudson N, Brandt M, Lopez FJ, Gale D, Luthert PJ, Adamson P, Turowski P, Stitt AW. Canning P, et al. Among authors: adamson p. Proc Natl Acad Sci U S A. 2016 Jun 28;113(26):7213-8. doi: 10.1073/pnas.1514213113. Epub 2016 Jun 13. Proc Natl Acad Sci U S A. 2016. PMID: 27298369 Free PMC article.
Spontaneous CNV in a novel mutant mouse is associated with early VEGF-A-driven angiogenesis and late-stage focal edema, neural cell loss, and dysfunction.
Nagai N, Lundh von Leithner P, Izumi-Nagai K, Hosking B, Chang B, Hurd R, Adamson P, Adamis AP, Foxton RH, Ng YS, Shima DT. Nagai N, et al. Among authors: adamson p. Invest Ophthalmol Vis Sci. 2014 May 20;55(6):3709-19. doi: 10.1167/iovs.14-13989. Invest Ophthalmol Vis Sci. 2014. PMID: 24845632 Free PMC article.
856 results