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Assessing skin sensitization hazard in mice and men using non-animal test methods.
Urbisch D, Mehling A, Guth K, Ramirez T, Honarvar N, Kolle S, Landsiedel R, Jaworska J, Kern PS, Gerberick F, Natsch A, Emter R, Ashikaga T, Miyazawa M, Sakaguchi H. Urbisch D, et al. Among authors: kern ps. Regul Toxicol Pharmacol. 2015 Mar;71(2):337-51. doi: 10.1016/j.yrtph.2014.12.008. Epub 2014 Dec 23. Regul Toxicol Pharmacol. 2015. PMID: 25541156 Free article.
TIMES-SS--a promising tool for the assessment of skin sensitization hazard. A characterization with respect to the OECD validation principles for (Q)SARs and an external evaluation for predictivity.
Patlewicz G, Dimitrov SD, Low LK, Kern PS, Dimitrova GD, Comber MI, Aptula AO, Phillips RD, Niemelä J, Madsen C, Wedebye EB, Roberts DW, Bailey PT, Mekenyan OG. Patlewicz G, et al. Among authors: kern ps. Regul Toxicol Pharmacol. 2007 Jul;48(2):225-39. doi: 10.1016/j.yrtph.2007.03.003. Epub 2007 Mar 25. Regul Toxicol Pharmacol. 2007. PMID: 17467128
Identifying and characterizing chemical skin sensitizers without animal testing: Colipa's research and method development program.
Aeby P, Ashikaga T, Bessou-Touya S, Schepky A, Gerberick F, Kern P, Marrec-Fairley M, Maxwell G, Ovigne JM, Sakaguchi H, Reisinger K, Tailhardat M, Martinozzi-Teissier S, Winkler P. Aeby P, et al. Toxicol In Vitro. 2010 Sep;24(6):1465-73. doi: 10.1016/j.tiv.2010.07.005. Epub 2010 Jul 17. Toxicol In Vitro. 2010. PMID: 20624454 Review.
Guiding principles for the implementation of non-animal safety assessment approaches for cosmetics: skin sensitisation.
Goebel C, Aeby P, Ade N, Alépée N, Aptula A, Araki D, Dufour E, Gilmour N, Hibatallah J, Keller D, Kern P, Kirst A, Marrec-Fairley M, Maxwell G, Rowland J, Safford B, Schellauf F, Schepky A, Seaman C, Teichert T, Tessier N, Teissier S, Weltzien HU, Winkler P, Scheel J. Goebel C, et al. Regul Toxicol Pharmacol. 2012 Jun;63(1):40-52. doi: 10.1016/j.yrtph.2012.02.007. Epub 2012 Feb 21. Regul Toxicol Pharmacol. 2012. PMID: 22374415 Free article.
59 results