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A functional genetic approach identifies the PI3K pathway as a major determinant of trastuzumab resistance in breast cancer.
Berns K, Horlings HM, Hennessy BT, Madiredjo M, Hijmans EM, Beelen K, Linn SC, Gonzalez-Angulo AM, Stemke-Hale K, Hauptmann M, Beijersbergen RL, Mills GB, van de Vijver MJ, Bernards R. Berns K, et al. Among authors: hennessy bt. Cancer Cell. 2007 Oct;12(4):395-402. doi: 10.1016/j.ccr.2007.08.030. Cancer Cell. 2007. PMID: 17936563 Free article. Clinical Trial.
The frequencies and clinical implications of mutations in 33 kinase-related genes in locally advanced rectal cancer: a pilot study.
Abdul-Jalil KI, Sheehan KM, Toomey S, Schmid J, Prehn J, O'Grady A, Cummins R, O'Neill B, McNamara DA, Deasy J, Breathnach O, Grogan L, Rogers A, Doherty G, Winter D, Ryan J, El-Masry S, Gibbons D, Sheahan K, Gillen P, Kay EW, Hennessy BT. Abdul-Jalil KI, et al. Among authors: hennessy bt. Ann Surg Oncol. 2014 Aug;21(8):2642-9. doi: 10.1245/s10434-014-3658-x. Epub 2014 Apr 4. Ann Surg Oncol. 2014. PMID: 24700299
Peroxiredoxin-1 protects estrogen receptor α from oxidative stress-induced suppression and is a protein biomarker of favorable prognosis in breast cancer.
O'Leary PC, Terrile M, Bajor M, Gaj P, Hennessy BT, Mills GB, Zagozdzon A, O'Connor DP, Brennan DJ, Connor K, Li J, Gonzalez-Angulo AM, Sun HD, Pu JX, Pontén F, Uhlén M, Jirström K, Nowis DA, Crown JP, Zagozdzon R, Gallagher WM. O'Leary PC, et al. Among authors: hennessy bt. Breast Cancer Res. 2014 Jul 10;16(4):R79. doi: 10.1186/bcr3691. Breast Cancer Res. 2014. PMID: 25011585 Free PMC article.
Immune effects of bevacizumab: killing two birds with one stone.
Elamin YY, Rafee S, Toomey S, Hennessy BT. Elamin YY, et al. Among authors: hennessy bt. Cancer Microenviron. 2015 Apr;8(1):15-21. doi: 10.1007/s12307-014-0160-8. Epub 2014 Oct 18. Cancer Microenviron. 2015. PMID: 25326055 Free PMC article.
209 results