Peralta R - Search Results

1

Knockdown of nuclear-retained long noncoding RNAs using modified DNA antisense oligonucleotides.

Zong X, Huang L, Tripathi V, Peralta R, Freier SM, Guo S, Prasanth KV. Zong X, et al. Among authors: peralta r. Methods Mol Biol. 2015;1262:321-31. doi: 10.1007/978-1-4939-2253-6_20. Methods Mol Biol. 2015. PMID: 25555591

2

Characterization of target mRNA reduction through in situ RNA hybridization in multiple organ systems following systemic antisense treatment in animals.

Hung G, Xiao X, Peralta R, Bhattacharjee G, Murray S, Norris D, Guo S, Monia BP. Hung G, et al. Among authors: peralta r. Nucleic Acid Ther. 2013 Dec;23(6):369-78. doi: 10.1089/nat.2013.0443. Epub 2013 Oct 26. Nucleic Acid Ther. 2013. PMID: 24161045

3

Allele-Specific Inhibition of Rhodopsin With an Antisense Oligonucleotide Slows Photoreceptor Cell Degeneration.

Murray SF, Jazayeri A, Matthes MT, Yasumura D, Yang H, Peralta R, Watt A, Freier S, Hung G, Adamson PS, Guo S, Monia BP, LaVail MM, McCaleb ML. Murray SF, et al. Among authors: peralta r. Invest Ophthalmol Vis Sci. 2015 Oct;56(11):6362-75. doi: 10.1167/iovs.15-16400. Invest Ophthalmol Vis Sci. 2015. PMID: 26436889 Free PMC article.

4

Unique O-methoxyethyl ribose-DNA chimeric oligonucleotide induces an atypical melanoma differentiation-associated gene 5-dependent induction of type I interferon response.

Burel SA, Machemer T, Ragone FL, Kato H, Cauntay P, Greenlee S, Salim A, Gaarde WA, Hung G, Peralta R, Freier SM, Henry SP. Burel SA, et al. Among authors: peralta r. J Pharmacol Exp Ther. 2012 Jul;342(1):150-62. doi: 10.1124/jpet.112.193789. Epub 2012 Apr 13. J Pharmacol Exp Ther. 2012. PMID: 22505629

5

Reducing TMPRSS6 ameliorates hemochromatosis and β-thalassemia in mice.

Guo S, Casu C, Gardenghi S, Booten S, Aghajan M, Peralta R, Watt A, Freier S, Monia BP, Rivella S. Guo S, et al. Among authors: peralta r. J Clin Invest. 2013 Apr;123(4):1531-41. doi: 10.1172/JCI66969. Epub 2013 Mar 25. J Clin Invest. 2013. PMID: 23524968 Free PMC article.

6

2'-O-methoxyethyl splice-switching oligos correct splicing from IVS2-745 β-thalassemia patient cells restoring HbA production and chain rebalance.

Dong A, Ghiaccio V, Motta I, Guo S, Peralta R, Freier SM, Watt A, Damle S, Ikawa Y, Jarocha D, Chappell M, Stephanou C, Delbini P, Chen C, Christou S, Kleanthous M, Smith-Whitley K, Manwani D, Casu C, Abdulmalik O, Cappellini MD, Rivella S, Breda L. Dong A, et al. Among authors: peralta r. Haematologica. 2019 May 1;106(5):1433-1442. doi: 10.3324/haematol.2019.226852. Haematologica. 2019. PMID: 32439726 Free PMC article.

7

Peripheral androgen receptor gene suppression rescues disease in mouse models of spinal and bulbar muscular atrophy.

Lieberman AP, Yu Z, Murray S, Peralta R, Low A, Guo S, Yu XX, Cortes CJ, Bennett CF, Monia BP, La Spada AR, Hung G. Lieberman AP, et al. Among authors: peralta r. Cell Rep. 2014 May 8;7(3):774-84. doi: 10.1016/j.celrep.2014.02.008. Epub 2014 Apr 16. Cell Rep. 2014. PMID: 24746732 Free PMC article.

8

Inhibition of the alternative complement pathway by antisense oligonucleotides targeting complement factor B improves lupus nephritis in mice.

Grossman TR, Hettrick LA, Johnson RB, Hung G, Peralta R, Watt A, Henry SP, Adamson P, Monia BP, McCaleb ML. Grossman TR, et al. Among authors: peralta r. Immunobiology. 2016 Jun;221(6):701-8. doi: 10.1016/j.imbio.2015.08.001. Epub 2015 Aug 10. Immunobiology. 2016. PMID: 26307001 Free article.

9

Cardiovascular and Metabolic Effects of ANGPTL3 Antisense Oligonucleotides.

Graham MJ, Lee RG, Brandt TA, Tai LJ, Fu W, Peralta R, Yu R, Hurh E, Paz E, McEvoy BW, Baker BF, Pham NC, Digenio A, Hughes SG, Geary RS, Witztum JL, Crooke RM, Tsimikas S. Graham MJ, et al. Among authors: peralta r. N Engl J Med. 2017 Jul 20;377(3):222-232. doi: 10.1056/NEJMoa1701329. Epub 2017 May 24. N Engl J Med. 2017. PMID: 28538111 Free article. Clinical Trial.

10

KLF4 is a FOXO target gene that suppresses B cell proliferation.

Yusuf I, Kharas MG, Chen J, Peralta RQ, Maruniak A, Sareen P, Yang VW, Kaestner KH, Fruman DA. Yusuf I, et al. Int Immunol. 2008 May;20(5):671-81. doi: 10.1093/intimm/dxn024. Epub 2008 Mar 28. Int Immunol. 2008. PMID: 18375530

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