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Pyruvate sensitizes pancreatic tumors to hypoxia-activated prodrug TH-302.
Wojtkowiak JW, Cornnell HC, Matsumoto S, Saito K, Takakusagi Y, Dutta P, Kim M, Zhang X, Leos R, Bailey KM, Martinez G, Lloyd MC, Weber C, Mitchell JB, Lynch RM, Baker AF, Gatenby RA, Rejniak KA, Hart C, Krishna MC, Gillies RJ. Wojtkowiak JW, et al. Among authors: baker af. Cancer Metab. 2015 Jan 29;3(1):2. doi: 10.1186/s40170-014-0026-z. eCollection 2015. Cancer Metab. 2015. PMID: 25635223 Free PMC article.
Reproducibility of magnetic resonance perfusion imaging.
Zhang X, Pagel MD, Baker AF, Gillies RJ. Zhang X, et al. Among authors: baker af. PLoS One. 2014 Feb 25;9(2):e89797. doi: 10.1371/journal.pone.0089797. eCollection 2014. PLoS One. 2014. PMID: 24587040 Free PMC article.
TH-302, a hypoxia-activated prodrug with broad in vivo preclinical combination therapy efficacy: optimization of dosing regimens and schedules.
Liu Q, Sun JD, Wang J, Ahluwalia D, Baker AF, Cranmer LD, Ferraro D, Wang Y, Duan JX, Ammons WS, Curd JG, Matteucci MD, Hart CP. Liu Q, et al. Among authors: baker af. Cancer Chemother Pharmacol. 2012 Jun;69(6):1487-98. doi: 10.1007/s00280-012-1852-8. Epub 2012 Mar 2. Cancer Chemother Pharmacol. 2012. PMID: 22382881 Free PMC article.
60 results