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Modeling the mechanisms of biological GTP hydrolysis.
Carvalho AT, Szeler K, Vavitsas K, Åqvist J, Kamerlin SC. Carvalho AT, et al. Arch Biochem Biophys. 2015 Sep 15;582:80-90. doi: 10.1016/j.abb.2015.02.027. Epub 2015 Feb 27. Arch Biochem Biophys. 2015. PMID: 25731854 Free article. Review.
Cooperativity and flexibility in enzyme evolution.
Pabis A, Risso VA, Sanchez-Ruiz JM, Kamerlin SC. Pabis A, et al. Curr Opin Struct Biol. 2018 Feb;48:83-92. doi: 10.1016/j.sbi.2017.10.020. Epub 2017 Nov 12. Curr Opin Struct Biol. 2018. PMID: 29141202 Free article. Review.
Evolution of chalcone isomerase from a noncatalytic ancestor.
Kaltenbach M, Burke JR, Dindo M, Pabis A, Munsberg FS, Rabin A, Kamerlin SCL, Noel JP, Tawfik DS. Kaltenbach M, et al. Among authors: kamerlin scl. Nat Chem Biol. 2018 Jun;14(6):548-555. doi: 10.1038/s41589-018-0042-3. Epub 2018 Apr 23. Nat Chem Biol. 2018. PMID: 29686356
The evolution of multiple active site configurations in a designed enzyme.
Hong NS, Petrović D, Lee R, Gryn'ova G, Purg M, Saunders J, Bauer P, Carr PD, Lin CY, Mabbitt PD, Zhang W, Altamore T, Easton C, Coote ML, Kamerlin SCL, Jackson CJ. Hong NS, et al. Among authors: kamerlin scl. Nat Commun. 2018 Sep 25;9(1):3900. doi: 10.1038/s41467-018-06305-y. Nat Commun. 2018. PMID: 30254369 Free PMC article.
149 results