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C2H2 zinc finger proteins greatly expand the human regulatory lexicon.
Najafabadi HS, Mnaimneh S, Schmitges FW, Garton M, Lam KN, Yang A, Albu M, Weirauch MT, Radovani E, Kim PM, Greenblatt J, Frey BJ, Hughes TR. Najafabadi HS, et al. Among authors: frey bj. Nat Biotechnol. 2015 May;33(5):555-62. doi: 10.1038/nbt.3128. Epub 2015 Feb 18. Nat Biotechnol. 2015. PMID: 25690854
A compendium of RNA-binding motifs for decoding gene regulation.
Ray D, Kazan H, Cook KB, Weirauch MT, Najafabadi HS, Li X, Gueroussov S, Albu M, Zheng H, Yang A, Na H, Irimia M, Matzat LH, Dale RK, Smith SA, Yarosh CA, Kelly SM, Nabet B, Mecenas D, Li W, Laishram RS, Qiao M, Lipshitz HD, Piano F, Corbett AH, Carstens RP, Frey BJ, Anderson RA, Lynch KW, Penalva LO, Lei EP, Fraser AG, Blencowe BJ, Morris QD, Hughes TR. Ray D, et al. Among authors: frey bj. Nature. 2013 Jul 11;499(7457):172-7. doi: 10.1038/nature12311. Nature. 2013. PMID: 23846655 Free PMC article.
Using expression profiling data to identify human microRNA targets.
Huang JC, Babak T, Corson TW, Chua G, Khan S, Gallie BL, Hughes TR, Blencowe BJ, Frey BJ, Morris QD. Huang JC, et al. Among authors: frey bj. Nat Methods. 2007 Dec;4(12):1045-9. doi: 10.1038/nmeth1130. Epub 2007 Nov 18. Nat Methods. 2007. PMID: 18026111
RNA splicing. The human splicing code reveals new insights into the genetic determinants of disease.
Xiong HY, Alipanahi B, Lee LJ, Bretschneider H, Merico D, Yuen RK, Hua Y, Gueroussov S, Najafabadi HS, Hughes TR, Morris Q, Barash Y, Krainer AR, Jojic N, Scherer SW, Blencowe BJ, Frey BJ. Xiong HY, et al. Among authors: frey bj. Science. 2015 Jan 9;347(6218):1254806. doi: 10.1126/science.1254806. Epub 2014 Dec 18. Science. 2015. PMID: 25525159 Free PMC article.
Identifying transcription factor functions and targets by phenotypic activation.
Chua G, Morris QD, Sopko R, Robinson MD, Ryan O, Chan ET, Frey BJ, Andrews BJ, Boone C, Hughes TR. Chua G, et al. Among authors: frey bj. Proc Natl Acad Sci U S A. 2006 Aug 8;103(32):12045-50. doi: 10.1073/pnas.0605140103. Epub 2006 Jul 31. Proc Natl Acad Sci U S A. 2006. PMID: 16880382 Free PMC article.
Functional coordination of alternative splicing in the mammalian central nervous system.
Fagnani M, Barash Y, Ip JY, Misquitta C, Pan Q, Saltzman AL, Shai O, Lee L, Rozenhek A, Mohammad N, Willaime-Morawek S, Babak T, Zhang W, Hughes TR, van der Kooy D, Frey BJ, Blencowe BJ. Fagnani M, et al. Among authors: frey bj. Genome Biol. 2007;8(6):R108. doi: 10.1186/gb-2007-8-6-r108. Genome Biol. 2007. PMID: 17565696 Free PMC article.
70 results