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Page 1
Design of small molecule epigenetic modulators.
Pachaiyappan B, Woster PM. Pachaiyappan B, et al. Bioorg Med Chem Lett. 2014 Jan 1;24(1):21-32. doi: 10.1016/j.bmcl.2013.11.001. Epub 2013 Nov 13. Bioorg Med Chem Lett. 2014. PMID: 24300735 Free PMC article. Review.
Interrogating alkyl and arylalkylpolyamino (bis)urea and (bis)thiourea isosteres as potent antimalarial chemotypes against multiple lifecycle forms of Plasmodium falciparum parasites.
Verlinden BK, de Beer M, Pachaiyappan B, Besaans E, Andayi WA, Reader J, Niemand J, van Biljon R, Guy K, Egan T, Woster PM, Birkholtz LM. Verlinden BK, et al. Among authors: pachaiyappan b. Bioorg Med Chem. 2015 Aug 15;23(16):5131-43. doi: 10.1016/j.bmc.2015.01.036. Epub 2015 Jan 28. Bioorg Med Chem. 2015. PMID: 25684422 Free PMC article.
Antibacterial Diamines Targeting Bacterial Membranes.
Wang B, Pachaiyappan B, Gruber JD, Schmidt MG, Zhang YM, Woster PM. Wang B, et al. Among authors: pachaiyappan b. J Med Chem. 2016 Apr 14;59(7):3140-51. doi: 10.1021/acs.jmedchem.5b01912. Epub 2016 Mar 28. J Med Chem. 2016. PMID: 26964758 Free PMC article.
Corrigendum to "Structure-activity study for (bis)ureidopropyl- and (bis)thioureidopropyldiamine LSD1 inhibitors with 3-5-3 and 3-6-3 carbon backbone architectures" [Bioorg. Med. Chem. 23 (2015) 1601-1612].
Nowotarski SL, Pachaiyappan B, Holshouser SL, Kutz CJ, Li Y, Huang Y, Sharma SK, Casero RA Jr, Woster PM. Nowotarski SL, et al. Among authors: pachaiyappan b. Bioorg Med Chem. 2018 Jul 23;26(12):3728-3729. doi: 10.1016/j.bmc.2018.05.032. Epub 2018 May 30. Bioorg Med Chem. 2018. PMID: 29859749 No abstract available.
Deciphering T Cell Immunometabolism with Activity-Based Protein Profiling.
Borne AL, Huang T, McCloud RL, Pachaiyappan B, Bullock TNJ, Hsu KL. Borne AL, et al. Among authors: pachaiyappan b. Curr Top Microbiol Immunol. 2019;420:175-210. doi: 10.1007/82_2018_124. Curr Top Microbiol Immunol. 2019. PMID: 30128827 Free PMC article. Review.