Beaumont K - Search Results

1

Smith DA, Beaumont K, Maurer TS, Di L. Smith DA, et al. Among authors: beaumont k. J Med Chem. 2015 Aug 13;58(15):5691-8. doi: 10.1021/acs.jmedchem.5b00201. Epub 2015 Apr 1. J Med Chem. 2015. PMID: 25799158

2

Relevance of Half-Life in Drug Design.

Smith DA, Beaumont K, Maurer TS, Di L. Smith DA, et al. Among authors: beaumont k. J Med Chem. 2018 May 24;61(10):4273-4282. doi: 10.1021/acs.jmedchem.7b00969. Epub 2017 Nov 17. J Med Chem. 2018. PMID: 29112446

3

Clearance in Drug Design.

Smith DA, Beaumont K, Maurer TS, Di L. Smith DA, et al. Among authors: beaumont k. J Med Chem. 2019 Mar 14;62(5):2245-2255. doi: 10.1021/acs.jmedchem.8b01263. Epub 2018 Oct 17. J Med Chem. 2019. PMID: 30281973 Review.

4

Dose Predictions for Drug Design.

Maurer TS, Smith D, Beaumont K, Di L. Maurer TS, et al. Among authors: beaumont k. J Med Chem. 2020 Jun 25;63(12):6423-6435. doi: 10.1021/acs.jmedchem.9b01365. Epub 2020 Jan 22. J Med Chem. 2020. PMID: 31913040

5

Oral delivery of G protein-coupled receptor modulators: an explanation for the observed class difference.

Beaumont K, Schmid E, Smith DA. Beaumont K, et al. Bioorg Med Chem Lett. 2005 Aug 15;15(16):3658-64. doi: 10.1016/j.bmcl.2005.05.042. Bioorg Med Chem Lett. 2005. PMID: 15982884 Review.

6

Does human pharmacokinetic prediction add significant value to compound selection in drug discovery research?

Beaumont K, Smith DA. Beaumont K, et al. Curr Opin Drug Discov Devel. 2009 Jan;12(1):61-71. Curr Opin Drug Discov Devel. 2009. PMID: 19152214

7

Property-based design: optimization of drug absorption and pharmacokinetics.

van De Waterbeemd H, Smith DA, Beaumont K, Walker DK. van De Waterbeemd H, et al. Among authors: beaumont k. J Med Chem. 2001 Apr 26;44(9):1313-33. doi: 10.1021/jm000407e. J Med Chem. 2001. PMID: 11311053 Review. No abstract available.

8

Prediction of human pharmacokinetics from preclinical information: comparative accuracy of quantitative prediction approaches.

Hosea NA, Collard WT, Cole S, Maurer TS, Fang RX, Jones H, Kakar SM, Nakai Y, Smith BJ, Webster R, Beaumont K. Hosea NA, et al. Among authors: beaumont k. J Clin Pharmacol. 2009 May;49(5):513-33. doi: 10.1177/0091270009333209. Epub 2009 Mar 19. J Clin Pharmacol. 2009. PMID: 19299532

9

In Vitro-In Vivo Extrapolation of Intestinal Availability for Carboxylesterase Substrates Using Portal Vein-Cannulated Monkey.

Trapa PE, Beaumont K, Atkinson K, Eng H, King-Ahmad A, Scott DO, Maurer TS, Di L. Trapa PE, et al. Among authors: beaumont k. J Pharm Sci. 2017 Mar;106(3):898-905. doi: 10.1016/j.xphs.2016.12.001. Epub 2016 Dec 18. J Pharm Sci. 2017. PMID: 27998705

10

Bioanalytical data in decision making: discovery and development.

Smith DA, Beaumont K, Cussans NJ, Humphrey MJ, Jezequel SG, Rance DJ, Stopher DA, Walker DK. Smith DA, et al. Among authors: beaumont k. Xenobiotica. 1992 Sep-Oct;22(9-10):1195-205. doi: 10.3109/00498259209051873. Xenobiotica. 1992. PMID: 1441610 Review.

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