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Targeting Nrf2 with the triterpenoid CDDO-imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice.
Sussan TE, Rangasamy T, Blake DJ, Malhotra D, El-Haddad H, Bedja D, Yates MS, Kombairaju P, Yamamoto M, Liby KT, Sporn MB, Gabrielson KL, Champion HC, Tuder RM, Kensler TW, Biswal S. Sussan TE, et al. Among authors: biswal s. Proc Natl Acad Sci U S A. 2009 Jan 6;106(1):250-5. doi: 10.1073/pnas.0804333106. Epub 2008 Dec 22. Proc Natl Acad Sci U S A. 2009. PMID: 19104057 Free PMC article.
Denitrosylation of HDAC2 by targeting Nrf2 restores glucocorticosteroid sensitivity in macrophages from COPD patients.
Malhotra D, Thimmulappa RK, Mercado N, Ito K, Kombairaju P, Kumar S, Ma J, Feller-Kopman D, Wise R, Barnes P, Biswal S. Malhotra D, et al. Among authors: biswal s. J Clin Invest. 2011 Nov;121(11):4289-302. doi: 10.1172/JCI45144. Epub 2011 Oct 17. J Clin Invest. 2011. Retraction in: J Clin Invest. 2014 Dec;124(12):5521. doi: 10.1172/JCI79606. PMID: 22005302 Free PMC article. Retracted.
Genetic silencing of Nrf2 enhances X-ROS in dysferlin-deficient muscle.
Kombairaju P, Kerr JP, Roche JA, Pratt SJP, Lovering RM, Sussan TE, Kim JH, Shi G, Biswal S, Ward CW. Kombairaju P, et al. Among authors: biswal s. Front Physiol. 2014 Feb 19;5:57. doi: 10.3389/fphys.2014.00057. eCollection 2014. Front Physiol. 2014. PMID: 24600403 Free PMC article.
Nrf2-Mediated Regulation of Skeletal Muscle Glycogen Metabolism.
Uruno A, Yagishita Y, Katsuoka F, Kitajima Y, Nunomiya A, Nagatomi R, Pi J, Biswal SS, Yamamoto M. Uruno A, et al. Among authors: biswal ss. Mol Cell Biol. 2016 May 16;36(11):1655-72. doi: 10.1128/MCB.01095-15. Print 2016 Jun 1. Mol Cell Biol. 2016. PMID: 27044864 Free PMC article.
551 results